FUT11 protein (Homo sapiens) - STRING network view

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FUT11

fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity) (492 aa)

Predicted Functional Partners:

FUT8

0.748

POFUT1

0.708

POFUT2

0.615

CCDC155

0.516

FUT2

0.490

TMEM150A

0.489

ST3GAL6

0.481

C10orf55

0.480

C9orf172

0.464

ST3GAL3

0.463

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
C10orf55	CCDC155	ENSP00000386960	ENSP00000404220	chromosome 10 open reading frame 55	coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity)	0.757
C10orf55	FUT11	ENSP00000386960	ENSP00000361932	chromosome 10 open reading frame 55	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	0.480
C9orf172	FUT11	ENSP00000412388	ENSP00000361932	chromosome 9 open reading frame 172	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	0.464
CCDC155	C10orf55	ENSP00000404220	ENSP00000386960	coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity)	chromosome 10 open reading frame 55	0.757
CCDC155	FUT11	ENSP00000404220	ENSP00000361932	coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity)	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	0.516
FUT11	C10orf55	ENSP00000361932	ENSP00000386960	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	chromosome 10 open reading frame 55	0.480
FUT11	C9orf172	ENSP00000361932	ENSP00000412388	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	chromosome 9 open reading frame 172	0.464
FUT11	CCDC155	ENSP00000361932	ENSP00000404220	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	coiled-coil domain containing 155; May be involved in meiotic chromosome dynamics and homolog pairing (By similarity)	0.516
FUT11	FUT2	ENSP00000361932	ENSP00000375748	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	fucosyltransferase 2 (secretor status included); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values	0.490
FUT11	FUT8	ENSP00000361932	ENSP00000353910	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity)	0.748
FUT11	POFUT1	ENSP00000361932	ENSP00000364902	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	protein O-fucosyltransferase 1; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue found in the consensus sequence C2-X(4,5)-[S/T]-C3 of EGF domains, where C2 and C3 are the second and third conserved cysteines. Specifically uses GDP-fucose as donor substrate and proper disulfide pairing of the substrate EGF domains is required for fucose transfer. Plays a crucial role in NOTCH signaling. Initial fucosylation of NOTCH by POFUT1 generates a substrate for FRINGE/RFNG, an acetylglucosaminyltransferase that can then extend [...]	0.708
FUT11	POFUT2	ENSP00000361932	ENSP00000339613	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	protein O-fucosyltransferase 2; Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X(2,3)-S/T-C2-X(2)-G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization [...]	0.615
FUT11	ST3GAL3	ENSP00000361932	ENSP00000262915	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.463
FUT11	ST3GAL6	ENSP00000361932	ENSP00000377717	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1	0.481
FUT11	TMEM150A	ENSP00000361932	ENSP00000334708	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	transmembrane protein 150A; Possible role in fasting-induced catabolism (By similarity)	0.489
FUT2	FUT11	ENSP00000375748	ENSP00000361932	fucosyltransferase 2 (secretor status included); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	0.490
FUT2	FUT8	ENSP00000375748	ENSP00000353910	fucosyltransferase 2 (secretor status included); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values	fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity)	0.617
FUT2	ST3GAL3	ENSP00000375748	ENSP00000262915	fucosyltransferase 2 (secretor status included); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values	ST3 beta-galactoside alpha-2,3-sialyltransferase 3	0.931
FUT2	ST3GAL6	ENSP00000375748	ENSP00000377717	fucosyltransferase 2 (secretor status included); Creates a soluble precursor oligosaccharide FuC-alpha ((1,2)Galbeta-) called the H antigen which is an essential substrate for the final step in the soluble A and B antigen synthesis pathway. H and Se enzymes fucosylate the same acceptor substrates but exhibit different Km values	ST3 beta-galactoside alpha-2,3-sialyltransferase 6; Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3- sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1	0.909
FUT8	FUT11	ENSP00000353910	ENSP00000361932	fucosyltransferase 8 (alpha (1,6) fucosyltransferase); Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans (By similarity)	fucosyltransferase 11 (alpha (1,3) fucosyltransferase); Probable fucosyltransferase (By similarity)	0.748

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