HPCAL4 protein (Homo sapiens) - STRING network view

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Score

HPCAL4

hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity) (191 aa)

Predicted Functional Partners:

PI4KB

0.864

FAM131C

0.590

TTC12

0.579

POTEE

0.541

POTEI

0.541

POTEJ

0.541

POTEF

0.541

DTX2

0.498

ANXA10

0.493

FBXL16

0.483

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANXA10	HPCAL4	ENSP00000352248	ENSP00000361935	annexin A10	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.493
DTX2	HPCAL4	ENSP00000322885	ENSP00000361935	deltex homolog 2 (Drosophila); Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.498
FAM131C	HPCAL4	ENSP00000364814	ENSP00000361935	family with sequence similarity 131, member C	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.590
FBXL16	HPCAL4	ENSP00000318674	ENSP00000361935	F-box and leucine-rich repeat protein 16; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity)	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.483
HPCAL4	ANXA10	ENSP00000361935	ENSP00000352248	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	annexin A10	0.493
HPCAL4	DTX2	ENSP00000361935	ENSP00000322885	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	deltex homolog 2 (Drosophila); Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity	0.498
HPCAL4	FAM131C	ENSP00000361935	ENSP00000364814	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	family with sequence similarity 131, member C	0.590
HPCAL4	FBXL16	ENSP00000361935	ENSP00000318674	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	F-box and leucine-rich repeat protein 16; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity)	0.483
HPCAL4	PI4KB	ENSP00000361935	ENSP00000271657	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	phosphatidylinositol 4-kinase, catalytic, beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity)	0.864
HPCAL4	POTEE	ENSP00000361935	ENSP00000439189	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	POTE ankyrin domain family member E	0.541
HPCAL4	POTEF	ENSP00000361935	ENSP00000350052	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	POTE ankyrin domain family, member F	0.541
HPCAL4	POTEI	ENSP00000361935	ENSP00000392718	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	POTE ankyrin domain family, member I	0.541
HPCAL4	POTEJ	ENSP00000361935	ENSP00000387176	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	POTE ankyrin domain family, member J	0.541
HPCAL4	TTC12	ENSP00000361935	ENSP00000433757	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	tetratricopeptide repeat domain 12	0.579
PI4KB	HPCAL4	ENSP00000271657	ENSP00000361935	phosphatidylinositol 4-kinase, catalytic, beta; Phosphorylates phosphatidylinositol (PI) in the first committed step in the production of the second messenger inositol- 1,4,5,-trisphosphate (PIP). May regulate Golgi disintegration/reorganization during mitosis, possibly via its phosphorylation. Involved in Golgi-to-plasma membrane trafficking (By similarity)	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.864
POTEE	HPCAL4	ENSP00000439189	ENSP00000361935	POTE ankyrin domain family member E	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.541
POTEF	HPCAL4	ENSP00000350052	ENSP00000361935	POTE ankyrin domain family, member F	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.541
POTEI	HPCAL4	ENSP00000392718	ENSP00000361935	POTE ankyrin domain family, member I	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.541
POTEJ	HPCAL4	ENSP00000387176	ENSP00000361935	POTE ankyrin domain family, member J	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.541
TTC12	HPCAL4	ENSP00000433757	ENSP00000361935	tetratricopeptide repeat domain 12	hippocalcin like 4; May be involved in the calcium-dependent regulation of rhodopsin phosphorylation (By similarity)	0.579

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