| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AASS | AMN | ENSP00000377040 | ENSP00000299155 | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | 0.537 |
| AASS | TMEM35 | ENSP00000377040 | ENSP00000362021 | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.485 |
| AMN | AASS | ENSP00000299155 | ENSP00000377040 | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | 0.537 |
| AMN | GRINA | ENSP00000299155 | ENSP00000314380 | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); Potential apoptotic regulator | 0.433 |
| AMN | SLC17A9 | ENSP00000299155 | ENSP00000359376 | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | solute carrier family 17, member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles | 0.485 |
| AMN | TMEM35 | ENSP00000299155 | ENSP00000362021 | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.584 |
| CENPJ | SASS6 | ENSP00000371308 | ENSP00000287482 | centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome | spindle assembly 6 homolog (C. elegans); Required for centrosome duplication. Overexpression results in excess foci-bearing centriolar markers | 0.997 |
| CENPJ | TMEM35 | ENSP00000371308 | ENSP00000362021 | centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.869 |
| GRINA | AMN | ENSP00000314380 | ENSP00000299155 | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); Potential apoptotic regulator | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | 0.433 |
| GRINA | TMEM35 | ENSP00000314380 | ENSP00000362021 | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); Potential apoptotic regulator | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.402 |
| NKX2-3 | TMEM35 | ENSP00000342828 | ENSP00000362021 | NK2 homeobox 3; Transcription factor (By similarity) | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.439 |
| SASS6 | CENPJ | ENSP00000287482 | ENSP00000371308 | spindle assembly 6 homolog (C. elegans); Required for centrosome duplication. Overexpression results in excess foci-bearing centriolar markers | centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome | 0.997 |
| SASS6 | TMEM35 | ENSP00000287482 | ENSP00000362021 | spindle assembly 6 homolog (C. elegans); Required for centrosome duplication. Overexpression results in excess foci-bearing centriolar markers | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.869 |
| SLC17A9 | AMN | ENSP00000359376 | ENSP00000299155 | solute carrier family 17, member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | 0.485 |
| SLC17A9 | TMEM35 | ENSP00000359376 | ENSP00000362021 | solute carrier family 17, member 9; Involved in vesicular storage and exocytosis of ATP. May accumulate ATP and other nucleotides in secretory vesicles such as adrenal chromaffin granules and synaptic vesicles | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | 0.485 |
| TMEM35 | AASS | ENSP00000362021 | ENSP00000377040 | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | aminoadipate-semialdehyde synthase; Bifunctional enzyme that catalyzes the first two steps in lysine degradation. The N-terminal and the C-terminal contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively | 0.485 |
| TMEM35 | AMN | ENSP00000362021 | ENSP00000299155 | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | amnionless homolog (mouse); Necessary for efficient absorption of vitamin B12. May direct the production of trunk mesoderm during development by modulating a bone morphogenetic protein (BMP) signaling pathway in the underlying visceral endoderm (By similarity) | 0.584 |
| TMEM35 | CENPJ | ENSP00000362021 | ENSP00000371308 | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | centromere protein J; Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome | 0.869 |
| TMEM35 | GRINA | ENSP00000362021 | ENSP00000314380 | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding); Potential apoptotic regulator | 0.402 |
| TMEM35 | NKX2-3 | ENSP00000362021 | ENSP00000342828 | transmembrane protein 35; A soluble peptide released by shedding may interact with NGFR and modulate neurite outgrowth (By similarity) | NK2 homeobox 3; Transcription factor (By similarity) | 0.439 |
Share
