C9orf16 protein (Homo sapiens) - STRING network view

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C9orf16

chromosome 9 open reading frame 16 (83 aa)

Predicted Functional Partners:

CEP290

0.608

C19orf66

0.589

ATP6V1E2

0.581

IKBIP

0.548

SDE2

0.483

ATP6V1D

0.483

THAP11

0.475

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V1D	ATP6V1E2	ENSP00000216442	ENSP00000304891	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity)	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity)	0.998
ATP6V1D	C9orf16	ENSP00000216442	ENSP00000362085	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity)	chromosome 9 open reading frame 16	0.483
ATP6V1E2	ATP6V1D	ENSP00000304891	ENSP00000216442	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity)	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity)	0.998
ATP6V1E2	C9orf16	ENSP00000304891	ENSP00000362085	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity)	chromosome 9 open reading frame 16	0.581
C19orf66	C9orf16	ENSP00000253110	ENSP00000362085	chromosome 19 open reading frame 66	chromosome 9 open reading frame 16	0.589
C19orf66	SDE2	ENSP00000253110	ENSP00000272091	chromosome 19 open reading frame 66	SDE2 telomere maintenance homolog (S. pombe)	0.483
C9orf16	ATP6V1D	ENSP00000362085	ENSP00000216442	chromosome 9 open reading frame 16	ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D; Subunit of the peripheral V1 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system (By similarity)	0.483
C9orf16	ATP6V1E2	ENSP00000362085	ENSP00000304891	chromosome 9 open reading frame 16	ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity)	0.581
C9orf16	C19orf66	ENSP00000362085	ENSP00000253110	chromosome 9 open reading frame 16	chromosome 19 open reading frame 66	0.589
C9orf16	CEP290	ENSP00000362085	ENSP00000448012	chromosome 9 open reading frame 16	centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes	0.608
C9orf16	IKBIP	ENSP00000362085	ENSP00000299157	chromosome 9 open reading frame 16	IKBKB interacting protein; Target of p53/TP53 with pro-apoptotic function	0.548
C9orf16	SDE2	ENSP00000362085	ENSP00000272091	chromosome 9 open reading frame 16	SDE2 telomere maintenance homolog (S. pombe)	0.483
C9orf16	THAP11	ENSP00000362085	ENSP00000304689	chromosome 9 open reading frame 16	THAP domain containing 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity)	0.475
CEP290	C9orf16	ENSP00000448012	ENSP00000362085	centrosomal protein 290kDa; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Activates ATF4-mediated transcription. Required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor cells; may play a role in ciliary transport processes	chromosome 9 open reading frame 16	0.608
IKBIP	C9orf16	ENSP00000299157	ENSP00000362085	IKBKB interacting protein; Target of p53/TP53 with pro-apoptotic function	chromosome 9 open reading frame 16	0.548
SDE2	C19orf66	ENSP00000272091	ENSP00000253110	SDE2 telomere maintenance homolog (S. pombe)	chromosome 19 open reading frame 66	0.483
SDE2	C9orf16	ENSP00000272091	ENSP00000362085	SDE2 telomere maintenance homolog (S. pombe)	chromosome 9 open reading frame 16	0.483
THAP11	C9orf16	ENSP00000304689	ENSP00000362085	THAP domain containing 11; Transcriptional repressor that plays a central role for embryogenesis and the pluripotency of embryonic stem (ES) cells. Sequence-specific DNA-binding factor that represses gene expression in pluripotent ES cells by directly binding to key genetic loci and recruiting epigenetic modifiers (By similarity)	chromosome 9 open reading frame 16	0.475

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