SLC25A25 protein (Homo sapiens) - STRING network view

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SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25 (503 aa)

Predicted Functional Partners:

HAND1

0.865

CRYAA

0.830

UBC

0.620

TMC8

0.614

SLC7A6OS

0.511

SLC20A2

0.479

YJEFN3

0.421

SLC25A4

0.412

SLC25A5

0.401

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRYAA	SLC25A25	ENSP00000291554	ENSP00000362159	crystallin, alpha A; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.830
HAND1	SLC25A25	ENSP00000231121	ENSP00000362159	heart and neural crest derivatives expressed 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5’- NRTCTG-3’ (non-canonical E-box) (By similarity)	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.865
SLC20A2	SLC25A25	ENSP00000340465	ENSP00000362159	solute carrier family 20 (phosphate transporter), member 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Fun [...]	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.479
SLC20A2	UBC	ENSP00000340465	ENSP00000344818	solute carrier family 20 (phosphate transporter), member 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Fun [...]	ubiquitin C	0.721
SLC25A25	CRYAA	ENSP00000362159	ENSP00000291554	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	crystallin, alpha A; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions	0.830
SLC25A25	HAND1	ENSP00000362159	ENSP00000231121	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	heart and neural crest derivatives expressed 1; Transcription factor that plays an essential role in both trophoblast-giant cells differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5’- NRTCTG-3’ (non-canonical E-box) (By similarity)	0.865
SLC25A25	SLC20A2	ENSP00000362159	ENSP00000340465	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	solute carrier family 20 (phosphate transporter), member 2; Sodium-phosphate symporter which seems to play a fundamental housekeeping role in phosphate transport by absorbing phosphate from interstitial fluid for normal cellular functions such as cellular metabolism, signal transduction, and nucleic acid and lipid synthesis. In vitro, sodium-dependent phosphate uptake is not siginificantly affected by acidic and alkaline conditions, however sodium-independent phosphate uptake occurs at acidic conditions. May play a role in extracellular matrix, cartilage and vascular calcification. Fun [...]	0.479
SLC25A25	SLC25A4	ENSP00000362159	ENSP00000281456	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane	0.412
SLC25A25	SLC25A5	ENSP00000362159	ENSP00000360671	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation	0.401
SLC25A25	SLC7A6OS	ENSP00000362159	ENSP00000263997	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	solute carrier family 7, member 6 opposite strand; Directs RNA polymerase II nuclear import (By similarity)	0.511
SLC25A25	TMC8	ENSP00000362159	ENSP00000325561	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	transmembrane channel-like 8; Probable ion channel (By similarity)	0.614
SLC25A25	UBC	ENSP00000362159	ENSP00000344818	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	ubiquitin C	0.620
SLC25A25	YJEFN3	ENSP00000362159	ENSP00000426964	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	YjeF N-terminal domain containing 3; May play a role in spermiogenesis and oogenesis	0.421
SLC25A4	SLC25A25	ENSP00000281456	ENSP00000362159	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.412
SLC25A4	UBC	ENSP00000281456	ENSP00000344818	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 4; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane	ubiquitin C	0.972
SLC25A5	SLC25A25	ENSP00000360671	ENSP00000362159	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.401
SLC25A5	UBC	ENSP00000360671	ENSP00000344818	solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation	ubiquitin C	0.995
SLC7A6OS	SLC25A25	ENSP00000263997	ENSP00000362159	solute carrier family 7, member 6 opposite strand; Directs RNA polymerase II nuclear import (By similarity)	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.511
TMC8	SLC25A25	ENSP00000325561	ENSP00000362159	transmembrane channel-like 8; Probable ion channel (By similarity)	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25	0.614
TMC8	YJEFN3	ENSP00000325561	ENSP00000426964	transmembrane channel-like 8; Probable ion channel (By similarity)	YjeF N-terminal domain containing 3; May play a role in spermiogenesis and oogenesis	0.450

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