| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| C10orf11 | C10orf35 | ENSP00000361577 | ENSP00000362376 | chromosome 10 open reading frame 11 | chromosome 10 open reading frame 35 | 0.499 |
| C10orf11 | SUPV3L1 | ENSP00000361577 | ENSP00000352678 | chromosome 10 open reading frame 11 | suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...] | 0.600 |
| C10orf35 | C10orf11 | ENSP00000362376 | ENSP00000361577 | chromosome 10 open reading frame 35 | chromosome 10 open reading frame 11 | 0.499 |
| C10orf35 | HERC4 | ENSP00000362376 | ENSP00000378624 | chromosome 10 open reading frame 35 | HECT and RLD domain containing E3 ubiquitin protein ligase 4; Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity) | 0.585 |
| C10orf35 | PBLD | ENSP00000362376 | ENSP00000308466 | chromosome 10 open reading frame 35 | phenazine biosynthesis-like protein domain containing | 0.570 |
| C10orf35 | SUPV3L1 | ENSP00000362376 | ENSP00000352678 | chromosome 10 open reading frame 35 | suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...] | 0.506 |
| C10orf35 | SYNE4 | ENSP00000362376 | ENSP00000316130 | chromosome 10 open reading frame 35 | spectrin repeat containing, nuclear envelope family member 4; Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity) | 0.414 |
| HERC4 | C10orf35 | ENSP00000378624 | ENSP00000362376 | HECT and RLD domain containing E3 ubiquitin protein ligase 4; Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity) | chromosome 10 open reading frame 35 | 0.585 |
| HERC4 | PBLD | ENSP00000378624 | ENSP00000308466 | HECT and RLD domain containing E3 ubiquitin protein ligase 4; Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity) | phenazine biosynthesis-like protein domain containing | 0.407 |
| PBLD | C10orf35 | ENSP00000308466 | ENSP00000362376 | phenazine biosynthesis-like protein domain containing | chromosome 10 open reading frame 35 | 0.570 |
| PBLD | HERC4 | ENSP00000308466 | ENSP00000378624 | phenazine biosynthesis-like protein domain containing | HECT and RLD domain containing E3 ubiquitin protein ligase 4; Probable E3 ubiquitin-protein ligase involved in either protein trafficking or in the distribution of cellular structures. Required for spermatozoon maturation and fertility, and for the removal of the cytoplasmic droplet of the spermatozoon. E3 ubiquitin-protein ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer it to targeted substrates (By similarity) | 0.407 |
| PBLD | SUPV3L1 | ENSP00000308466 | ENSP00000352678 | phenazine biosynthesis-like protein domain containing | suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...] | 0.449 |
| SUPV3L1 | C10orf11 | ENSP00000352678 | ENSP00000361577 | suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...] | chromosome 10 open reading frame 11 | 0.600 |
| SUPV3L1 | C10orf35 | ENSP00000352678 | ENSP00000362376 | suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...] | chromosome 10 open reading frame 35 | 0.506 |
| SUPV3L1 | PBLD | ENSP00000352678 | ENSP00000308466 | suppressor of var1, 3-like 1 (S. cerevisiae); Major helicase player in mitochondrial RNA metabolism. Component of the mitochondrial degradosome (mtEXO) complex, that degrades 3’ overhang double-stranded RNA with a 3’-to-5’ directionality in an ATP-dependent manner. ATPase and ATP- dependent multisubstrate helicase, able to unwind double stranded (ds) DNA and RNA, and RNA/DNA heteroduplexes in the 5’-to-3’ direction. Plays a role in the RNA surveillance system in mitochondria; regulates the stability of mature mRNAs, the removal of aberrantly formed mRNAs and the rapid degradation of no [...] | phenazine biosynthesis-like protein domain containing | 0.449 |
| SYNE4 | C10orf35 | ENSP00000316130 | ENSP00000362376 | spectrin repeat containing, nuclear envelope family member 4; Contributes to the establishment of secretory epithelial morphology by promoting kinesin-dependent apical migration of the centrosome and Golgi apparatus and basal localization of the nucleus (By similarity) | chromosome 10 open reading frame 35 | 0.414 |
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