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STRINGSTRING
GARNL3 GARNL3 LRSAM1 LRSAM1 KDM2A KDM2A FAM129B FAM129B FBXL19 FBXL19 LGALS4 LGALS4 ZBTB34 ZBTB34 EFHD2 EFHD2 KDM2B KDM2B XRN1 XRN1 LZTR1 LZTR1
"ZBTB34" - zinc finger and BTB domain containing 34 in Homo sapiens
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protein of unknown 3D structure
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second shell of interactors
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Predicted Interactions
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Score
ZBTB34zinc finger and BTB domain containing 34; May be a transcriptional repressor (500 aa)    
Predicted Functional Partners:
GARNL3
GTPase activating Rap/RanGAP domain-like 3 (1013 aa)
            score_image   0.727
LGALS4
lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions (323 aa)
            score_image   0.665
FAM129B
family with sequence similarity 129, member B; May play a role in apoptosis suppression. May promote melanoma cell invasion in vitro (746 aa)
            score_image   0.616
LRSAM1
leucine rich repeat and sterile alpha motif containing 1; E3 ubiquitin-protein ligase that mediates monoubiquitination of TSG101 at multiple sites, leading to inactivate the ability of TSG101 to sort endocytic (EGF receptors) and exocytic (HIV-1 viral proteins) cargos (723 aa)
        score_image   score_image   0.613
XRN1
5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) (1706 aa)
      score_image score_image   score_image   0.543
EFHD2
EF-hand domain family, member D2; May regulate B-cell receptor (BCR)-induced immature and primary B-cell apoptosis (By similarity). Plays a role as negative regulator of the canonical NF-kappa-B-activating branch (By similarity). Controls spontaneous apoptosis through the regulation of BCL2L1 abundance (By similarity) (240 aa)
            score_image   0.542
KDM2A
lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] (1162 aa)
        score_image   score_image   0.501
FBXL19
F-box and leucine-rich repeat protein 19; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) (694 aa)
        score_image   score_image   0.501
KDM2B
lysine (K)-specific demethylase 2B; Histone demethylase that demethylates ’Lys-4’ and ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 ’Lys-4’ and dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys-36’. Preferentially binds the transcribed region of ribosomal RNA and represses the transcription of ribosomal RNA genes which inhibits cell growth and proliferation. May also serve as a substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin [...] (1336 aa)
        score_image   score_image   0.501
LZTR1
leucine-zipper-like transcription regulator 1; Probable transcriptional regulator that may play a crucial role in embryogenesis (840 aa)
            score_image   0.486
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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