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STRINGSTRING
TSPYL4 TSPYL4 TSPY1 TSPY1 TSPYL6 TSPYL6 CYorf16 CYorf16 H2AFV H2AFV H2AFZ H2AFZ NAP1L6 NAP1L6 TSPY10 TSPY10 IPO9 IPO9 TSPY4 TSPY4 FAM197Y1 FAM197Y1
"NAP1L6" - nucleosome assembly protein 1-like 6 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NAP1L6nucleosome assembly protein 1-like 6 (107 aa)    
Predicted Functional Partners:
IPO9
importin 9 (1041 aa)
      score_image score_image   score_image   0.895
H2AFV
H2A histone family, member V; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] (128 aa)
        score_image   score_image   0.827
H2AFZ
H2A histone family, member Z; Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be [...] (128 aa)
        score_image   score_image   0.827
TSPYL6
TSPY-like 6 (410 aa)
      score_image score_image   score_image   0.696
TSPYL4
TSPY-like 4 (414 aa)
      score_image score_image   score_image   0.696
CYorf16
Uncharacterized protein (260 aa)
      score_image score_image   score_image   0.696
TSPY10
testis specific protein, Y-linked 10; Unknown. May be involved in sperm differentiation and proliferation (By similarity) (308 aa)
      score_image score_image   score_image   0.696
TSPY1
testis specific protein, Y-linked 1; May be involved in sperm differentiation and proliferation (308 aa)
      score_image score_image   score_image   0.696
FAM197Y1
family with sequence similarity 197, Y-linked, member 1 (259 aa)
      score_image score_image   score_image   0.696
TSPY4
testis specific protein, Y-linked 4; Unknown. May be involved in sperm differentiation and proliferation (By similarity) (314 aa)
      score_image score_image   score_image   0.696
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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