PI16 protein (Homo sapiens) - STRING network view

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PI16

peptidase inhibitor 16; Putative serine protease inhibitor (By similarity) (463 aa)

Predicted Functional Partners:

GYLTL1B

0.801

MANBA

0.643

EZH2

0.561

TGFBI

0.536

STARD10

0.529

ING1

0.525

STARD7

0.493

AVL9

0.433

GDPD2

0.432

ACOXL

0.430

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOXL	GDPD2	ENSP00000407761	ENSP00000414019	acyl-CoA oxidase-like	glycerophosphodiester phosphodiesterase domain containing 2; Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity)	0.738
ACOXL	PI16	ENSP00000407761	ENSP00000362778	acyl-CoA oxidase-like	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.430
AVL9	PI16	ENSP00000315568	ENSP00000362778	AVL9 homolog (S. cerevisiase); Functions in cell migration	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.433
EZH2	PI16	ENSP00000320147	ENSP00000362778	enhancer of zeste homolog 2 (Drosophila)	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.561
GDPD2	ACOXL	ENSP00000414019	ENSP00000407761	glycerophosphodiester phosphodiesterase domain containing 2; Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity)	acyl-CoA oxidase-like	0.738
GDPD2	PI16	ENSP00000414019	ENSP00000362778	glycerophosphodiester phosphodiesterase domain containing 2; Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity)	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.432
GYLTL1B	PI16	ENSP00000324570	ENSP00000362778	glycosyltransferase-like 1B; Glycosyltransferase which participates in glycosylation of alpha-dystroglycan. May carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. Has a higher activity toward alpha-dystroglycan than LARGE	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.801
ING1	PI16	ENSP00000364929	ENSP00000362778	inhibitor of growth family, member 1	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.525
MANBA	PI16	ENSP00000226578	ENSP00000362778	mannosidase, beta A, lysosomal; Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.643
PI16	ACOXL	ENSP00000362778	ENSP00000407761	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	acyl-CoA oxidase-like	0.430
PI16	AVL9	ENSP00000362778	ENSP00000315568	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	AVL9 homolog (S. cerevisiase); Functions in cell migration	0.433
PI16	EZH2	ENSP00000362778	ENSP00000320147	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	enhancer of zeste homolog 2 (Drosophila)	0.561
PI16	GDPD2	ENSP00000362778	ENSP00000414019	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	glycerophosphodiester phosphodiesterase domain containing 2; Has glycerophosphoinositol inositolphosphodiesterase activity and specifically hydrolyzes glycerophosphoinositol, with no activity for other substrates such as glycerophosphoinositol 4- phosphate, glycerophosphocholine, glycerophosphoethanolamine, and glycerophosphoserine. Accelerates the program of osteoblast differentiation and growth. May play a role in remodeling of the actin cytoskeleton (By similarity)	0.432
PI16	GYLTL1B	ENSP00000362778	ENSP00000324570	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	glycosyltransferase-like 1B; Glycosyltransferase which participates in glycosylation of alpha-dystroglycan. May carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. Has a higher activity toward alpha-dystroglycan than LARGE	0.801
PI16	ING1	ENSP00000362778	ENSP00000364929	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	inhibitor of growth family, member 1	0.525
PI16	MANBA	ENSP00000362778	ENSP00000226578	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	mannosidase, beta A, lysosomal; Exoglycosidase that cleaves the single beta-linked mannose residue from the non-reducing end of all N-linked glycoprotein oligosaccharides	0.643
PI16	STARD10	ENSP00000362778	ENSP00000335247	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes	0.529
PI16	STARD7	ENSP00000362778	ENSP00000338030	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	StAR-related lipid transfer (START) domain containing 7	0.493
PI16	TGFBI	ENSP00000362778	ENSP00000416330	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	transforming growth factor, beta-induced, 68kDa	0.536
STARD10	PI16	ENSP00000335247	ENSP00000362778	StAR-related lipid transfer (START) domain containing 10; May play metabolic roles in sperm maturation or fertilization (By similarity). Phospholipid transfer protein that preferentially selects lipid species containing a palmitoyl or stearoyl chain on the sn-1 and an unsaturated fatty acyl chain (18-1 or 18-2) on the sn-2 position. Able to transfer phosphatidylcholine (PC) and phosphatidyetanolamline (PE) between membranes	peptidase inhibitor 16; Putative serine protease inhibitor (By similarity)	0.529

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