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STRINGSTRING
TAF1 TAF1 EHHADH EHHADH ACER3 ACER3 ACRC ACRC VPS13A VPS13A MASTL MASTL CHEK2 CHEK2
"ACRC" - acidic repeat containing in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACRCacidic repeat containing (691 aa)    
Predicted Functional Partners:
ACER3
alkaline ceramidase 3; Hydrolyzes only phytoceramide into phytosphingosine and free fatty acid. Does not have reverse activity (267 aa)
             score_image   0.627
EHHADH
enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase (723 aa)
             score_image   0.598
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae) (3174 aa)
             score_image   0.597
MASTL
microtubule associated serine/threonine kinase-like; Serine/threonine kinase that plays a key role in M phase by acting as a regulator of mitosis entry and maintenance. Acts by promoting the inactivation of protein phosphatase 2A (PP2A) during M phase- does not directly inhibit PP2A but acts by mediating phosphorylation and subsequent activation of ARPP19 and ENSA at ’Ser-62’ and ’Ser-67’, respectively. ARPP19 and ENSA are phosphatase inhibitors that specifically inhibit the PPP2R2D (PR55-delta) subunit of PP2A. Inactivation of PP2A during M phase is essential to keep cyclin-B1-CDK1 ac [...] (879 aa)
       score_image         0.579
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa (1893 aa)
             score_image   0.562
CHEK2
checkpoint kinase 2 (586 aa)
       score_image         0.436
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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