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STRINGSTRING
TMEM67 TMEM67 FABP3 FABP3 NKAIN1 NKAIN1 LGALS4 LGALS4 COG2 COG2 SERINC2 SERINC2 TCP11L2 TCP11L2 WDR35 WDR35 KCNS1 KCNS1 LAPTM4A LAPTM4A MATN4 MATN4
"SERINC2" - serine incorporator 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SERINC2serine incorporator 2 (464 aa)    
Predicted Functional Partners:
COG2
component of oligomeric golgi complex 2; Required for normal Golgi morphology and function (738 aa)
            score_image   0.596
LAPTM4A
lysosomal protein transmembrane 4 alpha; May function in the transport of nucleosides and/or nucleoside derivatives between the cytosol and the lumen of an intracellular membrane-bound compartment (By similarity) (233 aa)
      score_image     score_image   0.593
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor); FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters (133 aa)
            score_image   0.574
NKAIN1
Na+/K+ transporting ATPase interacting 1 (207 aa)
            score_image   0.561
KCNS1
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 1; Potassium channel subunit. Modulates channel activity and reduces the ion flow (By similarity) (526 aa)
            score_image   0.557
MATN4
matrilin 4 (581 aa)
            score_image   0.505
TCP11L2
t-complex 11, testis-specific-like 2 (519 aa)
      score_image     score_image   0.472
TMEM67
transmembrane protein 67; Part of the tectonic-like complex which is required for tissue-specific ciliogenesis and may regulate ciliary membrane composition (By similarity). Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology. Essential for endoplasmic reticulum-associated degradation (ERAD) of surfactant protein C (SFTPC) (995 aa)
            score_image   0.469
LGALS4
lectin, galactoside-binding, soluble, 4; Galectin that binds lactose and a related range of sugars. May be involved in the assembly of adherens junctions (323 aa)
            score_image   0.465
WDR35
WD repeat domain 35; Component of the IFT complex A (IFT-A), a complex required for retrograde ciliary transport. Required for ciliogenesis. May promote CASP3 activation and TNF-stimulated apoptosis (1181 aa)
            score_image   0.461
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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