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STRINGSTRING
LPGAT1 LPGAT1 ANO6 ANO6 TRIAP1 TRIAP1 XKR8 XKR8 TAMM41 TAMM41 CIB2 CIB2 CNPY4 CNPY4 C16orf88 C16orf88
"XKR8" - XK, Kell blood group complex subunit-related family, member 8 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
XKR8XK, Kell blood group complex subunit-related family, member 8 (395 aa)    
Predicted Functional Partners:
ANO6
anoctamin 6; Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes (931 aa)
            score_image   0.651
TAMM41
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) (316 aa)
            score_image   0.614
CNPY4
canopy 4 homolog (zebrafish); Plays a role in the regulation of the cell surface expression of TLR4 (248 aa)
            score_image   0.590
C16orf88
chromosome 16 open reading frame 88 (458 aa)
            score_image   0.590
TRIAP1
TP53 regulated inhibitor of apoptosis 1; Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis (76 aa)
            score_image   0.551
LPGAT1
lysophosphatidylglycerol acyltransferase 1; Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor (370 aa)
            score_image   0.533
CIB2
calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) (187 aa)
            score_image   0.450
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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