node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANO6 | XKR8 | ENSP00000409126 | ENSP00000362991 | anoctamin 6; Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes | XK, Kell blood group complex subunit-related family, member 8 | 0.651 |
C16orf88 | CNPY4 | ENSP00000219837 | ENSP00000262932 | chromosome 16 open reading frame 88 | canopy 4 homolog (zebrafish); Plays a role in the regulation of the cell surface expression of TLR4 | 0.505 |
C16orf88 | XKR8 | ENSP00000219837 | ENSP00000362991 | chromosome 16 open reading frame 88 | XK, Kell blood group complex subunit-related family, member 8 | 0.590 |
CIB2 | XKR8 | ENSP00000258930 | ENSP00000362991 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | XK, Kell blood group complex subunit-related family, member 8 | 0.450 |
CNPY4 | C16orf88 | ENSP00000262932 | ENSP00000219837 | canopy 4 homolog (zebrafish); Plays a role in the regulation of the cell surface expression of TLR4 | chromosome 16 open reading frame 88 | 0.505 |
CNPY4 | XKR8 | ENSP00000262932 | ENSP00000362991 | canopy 4 homolog (zebrafish); Plays a role in the regulation of the cell surface expression of TLR4 | XK, Kell blood group complex subunit-related family, member 8 | 0.590 |
LPGAT1 | TAMM41 | ENSP00000355963 | ENSP00000273037 | lysophosphatidylglycerol acyltransferase 1; Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | 0.418 |
LPGAT1 | XKR8 | ENSP00000355963 | ENSP00000362991 | lysophosphatidylglycerol acyltransferase 1; Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor | XK, Kell blood group complex subunit-related family, member 8 | 0.533 |
TAMM41 | LPGAT1 | ENSP00000273037 | ENSP00000355963 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | lysophosphatidylglycerol acyltransferase 1; Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor | 0.418 |
TAMM41 | TRIAP1 | ENSP00000273037 | ENSP00000449795 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | TP53 regulated inhibitor of apoptosis 1; Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis | 0.610 |
TAMM41 | XKR8 | ENSP00000273037 | ENSP00000362991 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | XK, Kell blood group complex subunit-related family, member 8 | 0.614 |
TRIAP1 | TAMM41 | ENSP00000449795 | ENSP00000273037 | TP53 regulated inhibitor of apoptosis 1; Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | 0.610 |
TRIAP1 | XKR8 | ENSP00000449795 | ENSP00000362991 | TP53 regulated inhibitor of apoptosis 1; Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis | XK, Kell blood group complex subunit-related family, member 8 | 0.551 |
XKR8 | ANO6 | ENSP00000362991 | ENSP00000409126 | XK, Kell blood group complex subunit-related family, member 8 | anoctamin 6; Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes | 0.651 |
XKR8 | C16orf88 | ENSP00000362991 | ENSP00000219837 | XK, Kell blood group complex subunit-related family, member 8 | chromosome 16 open reading frame 88 | 0.590 |
XKR8 | CIB2 | ENSP00000362991 | ENSP00000258930 | XK, Kell blood group complex subunit-related family, member 8 | calcium and integrin binding family member 2; Critical for proper photorecetor cell maintenance and function. May play a role in calcium homeostasis and participate in calcium regulation in the mechanotransduction process (By similarity) | 0.450 |
XKR8 | CNPY4 | ENSP00000362991 | ENSP00000262932 | XK, Kell blood group complex subunit-related family, member 8 | canopy 4 homolog (zebrafish); Plays a role in the regulation of the cell surface expression of TLR4 | 0.590 |
XKR8 | LPGAT1 | ENSP00000362991 | ENSP00000355963 | XK, Kell blood group complex subunit-related family, member 8 | lysophosphatidylglycerol acyltransferase 1; Lysophoshatidylglycerol (LPG) specific acyltransferase that recognizes various acyl-CoAs and LPGs as substrates but demonstrates a clear preference for long chain saturated fatty acyl-CoAs and oleoyl-CoA as acyl donors. Prefers oleoyl-LPG over palmitoyl-LPG as an acyl receptor and oleoyl-CoA over lauroyl-CoA as an acyl donor | 0.533 |
XKR8 | TAMM41 | ENSP00000362991 | ENSP00000273037 | XK, Kell blood group complex subunit-related family, member 8 | TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae); May be involved in the translocation of transit peptide- containing proteins across the mitochondrial inner membrane (By similarity) | 0.614 |
XKR8 | TRIAP1 | ENSP00000362991 | ENSP00000449795 | XK, Kell blood group complex subunit-related family, member 8 | TP53 regulated inhibitor of apoptosis 1; Mediates cell survival by inhibiting activation of caspase-9 which prevents induction of apoptosis | 0.551 |