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STRINGSTRING
LAMA2 LAMA2 LAMA3 LAMA3 LAMA5 LAMA5 LAMC1 LAMC1 LAMA1 LAMA1 NTNG1 NTNG1 MEGF9 MEGF9 CA13 CA13 POLR3K POLR3K
"MEGF9" - multiple EGF-like-domains 9 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
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Cooccurence
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Experiments
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Textmining
[Homology]
Score
MEGF9multiple EGF-like-domains 9 (602 aa)    
Predicted Functional Partners:
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein [...] (108 aa)
            score_image   0.660
CA13
carbonic anhydrase XIII; Reversible hydration of carbon dioxide (262 aa)
            score_image   0.510
NTNG1
netrin G1; Involved in controlling patterning and neuronal circuit formation at the laminar, cellular, subcellular and synaptic levels. Promotes neurite outgrowth of both axons and dendrites (539 aa)
      score_image     score_image score_image 0.419
LAMA3
laminin, alpha 3; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3333 aa)
      score_image score_image   score_image score_image 0.413
LAMC1
laminin, gamma 1 (formerly LAMB2); Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (1609 aa)
      score_image score_image   score_image score_image 0.412
LAMA5
laminin, alpha 5; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3695 aa)
      score_image score_image   score_image score_image 0.412
LAMA2
laminin, alpha 2; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3122 aa)
      score_image score_image   score_image score_image 0.410
LAMA1
laminin, alpha 1; Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components (3075 aa)
      score_image score_image   score_image score_image 0.406
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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