Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CBX3 | MNF1 | ENSP00000336687 | ENSP00000363348 | chromobox homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ’Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins | mitochondrial nucleoid factor 1 | 0.493 |
HUNK | MNF1 | ENSP00000270112 | ENSP00000363348 | hormonally up-regulated Neu-associated kinase | mitochondrial nucleoid factor 1 | 0.503 |
IGF1 | MNF1 | ENSP00000302665 | ENSP00000363348 | insulin-like growth factor 1 (somatomedin C); The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake | mitochondrial nucleoid factor 1 | 0.810 |
MNF1 | CBX3 | ENSP00000363348 | ENSP00000336687 | mitochondrial nucleoid factor 1 | chromobox homolog 3; Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at ’Lys-9’, leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins | 0.493 |
MNF1 | HUNK | ENSP00000363348 | ENSP00000270112 | mitochondrial nucleoid factor 1 | hormonally up-regulated Neu-associated kinase | 0.503 |
MNF1 | IGF1 | ENSP00000363348 | ENSP00000302665 | mitochondrial nucleoid factor 1 | insulin-like growth factor 1 (somatomedin C); The insulin-like growth factors, isolated from plasma, are structurally and functionally related to insulin but have a much higher growth-promoting activity. May be a physiological regulator of [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblasts. Stimulates glucose transport in rat bone-derived osteoblastic (PyMS) cells and is effective at much lower concentrations than insulin, not only regarding glycogen and DNA synthesis but also with regard to enhancing glucose uptake | 0.810 |
MNF1 | NF1 | ENSP00000363348 | ENSP00000351015 | mitochondrial nucleoid factor 1 | neurofibromin 1; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity | 0.471 |
MNF1 | PHF5A | ENSP00000363348 | ENSP00000216252 | mitochondrial nucleoid factor 1 | PHD finger protein 5A; Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER- alpha. Also involved in pre-mRNA splicing | 0.500 |
MNF1 | SMUG1 | ENSP00000363348 | ENSP00000338606 | mitochondrial nucleoid factor 1 | single-strand-selective monofunctional uracil-DNA glycosylase 1; Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5- hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hyd [...] | 0.416 |
MNF1 | UQCC | ENSP00000363348 | ENSP00000363506 | mitochondrial nucleoid factor 1 | ubiquinol-cytochrome c reductase complex chaperone | 0.710 |
NF1 | MNF1 | ENSP00000351015 | ENSP00000363348 | neurofibromin 1; Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity | mitochondrial nucleoid factor 1 | 0.471 |
PHF5A | MNF1 | ENSP00000216252 | ENSP00000363348 | PHD finger protein 5A; Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER- alpha. Also involved in pre-mRNA splicing | mitochondrial nucleoid factor 1 | 0.500 |
SMUG1 | MNF1 | ENSP00000338606 | ENSP00000363348 | single-strand-selective monofunctional uracil-DNA glycosylase 1; Responsible for recognizing base lesions in the genome and initiating base excision DNA repair. Acts as a monofunctional DNA glycosylase specific for uracil (U) residues in DNA and has a preference for single-stranded DNA substrates. The activity is greater against mismatches (U/G) than against matches (U/A). Excised uracil (U), 5-formyluracil (fU) and uracil derivatives bearing an oxidized group at C5 [5-hydroxyuracil (hoU) and 5- hydroxymethyluracil (hmU)] in ssDNA and dsDNA but not analogous cytosine derivatives (5-hyd [...] | mitochondrial nucleoid factor 1 | 0.416 |
UQCC | MNF1 | ENSP00000363506 | ENSP00000363348 | ubiquinol-cytochrome c reductase complex chaperone | mitochondrial nucleoid factor 1 | 0.710 |