Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small nodes:
protein of unknown 3D structure
protein of unknown 3D structure
large nodes:
some 3D structure is known or predicted
some 3D structure is known or predicted
Node Color
colored nodes:
query proteins and first shell of interactors
query proteins and first shell of interactors
white nodes:
second shell of interactors
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Your Input:
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Neighborhood |
Gene Fusion |
Cooccurence |
Coexpression |
Experiments |
Databases |
Textmining |
[Homology] |
Score |
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 | PDIK1L | PDLIM1 interacting kinase 1 like (341 aa) | ||||||||||||
Predicted Functional Partners:
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 | ATG9A | autophagy related 9A (839 aa) |
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0.883 | |||||||||
 | GABARAPL3 | GABA(A) receptors associated protein like 3, pseudogene (117 aa) |
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0.741 | ||||||||
 | MAP1LC3A | microtubule-associated protein 1 light chain 3 alpha; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa) |
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0.741 | ||||||||
 | MAP1LC3C | microtubule-associated protein 1 light chain 3 gamma; Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity) (147 aa) |
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0.741 | ||||||||
 | GABARAP | GABA(A) receptor-associated protein; May play a role in intracellular transport of GABA(A) receptors and its interaction with the cytoskeleton. Involved in apoptosis. Involved in autophagy (By similarity) (117 aa) |
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0.741 | ||||||||
 | MAP1LC3B2 | microtubule-associated protein 1 light chain 3 beta 2; Probably involved in formation of autophagosomal vacuoles (autophagosomes) (By similarity) (125 aa) |
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0.741 | ||||||||
 | MAP1LC3B | microtubule-associated protein 1 light chain 3 beta; Involved in formation of autophagosomal vacuoles (autophagosomes) (125 aa) |
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0.741 | ||||||||
 | GABARAPL1 | GABA(A) receptor-associated protein like 1; Increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. Involved in formation of autophagosomal vacuoles (117 aa) |
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0.741 | ||||||||
 | GABARAPL2 | GABA(A) receptor-associated protein-like 2; Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1 (By similarity). Involved in autophagy (By similarity) (117 aa) |
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0.741 | ||||||||
 | ATG2A | autophagy related 2A; Required for both autophagosome formation and regulation of lipid droplet morphology and dispersion (1938 aa) |
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0.741 | ||||||||||
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Other names: H. sapiens, Homo, Homo sapiens, human, man
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