Full Link:
  • Version:
  • 10.0 (archived version)
STRINGSTRING
HSD17B8 HSD17B8 ERGIC2 ERGIC2 SLC39A7 SLC39A7 SLC30A5 SLC30A5 SLC30A7 SLC30A7 SLC39A3 SLC39A3 SLC30A6 SLC30A6 SLC39A1 SLC39A1 SLC39A9 SLC39A9 SLC30A10 SLC30A10 SLC30A1 SLC30A1
"SLC39A7" - solute carrier family 39 (zinc transporter), member 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SLC39A7solute carrier family 39 (zinc transporter), member 7 (469 aa)    
Predicted Functional Partners:
SLC30A5
solute carrier family 30 (zinc transporter), member 5; Functions as a zinc transporter. May be a transporter of zinc into beta cells in order to form insulin crystals. Partly regulates cellular zinc homeostasis. Required with ZNT7 for the activation of zinc-requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT6 and ZNT7 for the activation of TNAP (765 aa)
        score_image   score_image   0.812
SLC30A7
solute carrier family 30 (zinc transporter), member 7; Seems to facilitate zinc transport from the cytoplasm into the Golgi apparatus. Partly regulates cellular zinc homeostasis. Required with ZNT5 for the activation of zinc- requiring enzymes, alkaline phosphatases (ALPs). Transports zinc into the lumens of the Golgi apparatus and the vesicular compartments where ALPs locate, thus, converting apoALPs to holoALPs. Required with ZNT5 and ZNT6 for the activation of TNAP (By similarity) (376 aa)
        score_image   score_image   0.777
HSD17B8
hydroxysteroid (17-beta) dehydrogenase 8 (261 aa)
            score_image   0.763
SLC30A6
solute carrier family 30 (zinc transporter), member 6; Zinc-efflux transporter which allocates the cytoplasmic zinc to the trans-Golgi network (TGN) as well as the vesicular compartment (By similarity) (501 aa)
        score_image   score_image   0.744
SLC39A1
solute carrier family 39 (zinc transporter), member 1; Mediates zinc uptake. May function as a major endogenous zinc uptake transporter in many cells of the body. Responsible for the rapid uptake and accumulation of physiologically effective zinc in prostate cells (324 aa)
        score_image   score_image   0.680
SLC39A3
solute carrier family 39 (zinc transporter), member 3; Acts as a zinc-influx transporter (Potential) (314 aa)
        score_image   score_image   0.675
SLC30A1
solute carrier family 30 (zinc transporter), member 1; May be involved in zinc transport out of the cell (507 aa)
        score_image   score_image   0.662
SLC39A9
solute carrier family 39 (zinc transporter), member 9; May act as a zinc-influx transporter (By similarity) (307 aa)
            score_image   0.658
SLC30A10
solute carrier family 30, member 10; May be involved in zinc transport out of the cell, being a zinc-efflux transporter (By similarity) (485 aa)
        score_image   score_image   0.634
ERGIC2
ERGIC and golgi 2; Possible role in transport between endoplasmic reticulum and Golgi (By similarity) (377 aa)
            score_image   0.626
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
Server load: low (24%)