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FBP2 FBP2 GAPDH GAPDH TKT TKT ALDOB ALDOB GPI GPI PFKL PFKL PFKP PFKP PFKM PFKM PKM PKM ENO3 ENO3 GAPDHS GAPDHS
"ALDOB" - aldolase B, fructose-bisphosphate in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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Predicted Interactions
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protein homology
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Score
ALDOBaldolase B, fructose-bisphosphate (364 aa)    
Predicted Functional Partners:
PFKL
phosphofructokinase, liver; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP (780 aa)
      score_image   score_image score_image   0.988
PFKM
phosphofructokinase, muscle; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP (851 aa)
      score_image   score_image score_image   0.988
PFKP
phosphofructokinase, platelet; Catalyzes the third step of glycolysis, the phosphorylation of fructose-6-phosphate (F6P) by ATP to generate fructose-1,6-bisphosphate (FBP) and ADP (784 aa)
      score_image   score_image score_image   0.988
PKM
pyruvate kinase, muscle (531 aa)
      score_image   score_image score_image   0.984
GAPDH
glyceraldehyde-3-phosphate dehydrogenase; Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations throu [...] (335 aa)
score_image     score_image score_image score_image score_image   0.982
ENO3
enolase 3 (beta, muscle); Appears to have a function in striated muscle development and regeneration (434 aa)
      score_image   score_image score_image   0.981
GPI
glucose-6-phosphate isomerase; Besides it’s role as a glycolytic enzyme, mammalian GPI can function as a tumor-secreted cytokine and an angiogenic factor (AMF) that stimulates endothelial cell motility. GPI is also a neurotrophic factor (Neuroleukin) for spinal and sensory neurons (569 aa)
      score_image   score_image score_image   0.980
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic; May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity) (408 aa)
score_image     score_image score_image score_image score_image   0.974
TKT
transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate (623 aa)
score_image     score_image   score_image score_image   0.964
FBP2
fructose-1,6-bisphosphatase 2 (339 aa)
      score_image   score_image score_image   0.962
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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