FAAH2 protein (Homo sapiens) - STRING network view

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FAAH2

fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates (532 aa)

Predicted Functional Partners:

PET112

0.941

GPKOW

0.732

TMEM106C

0.720

PEPD

0.612

EPRS

0.571

ARMCX3

0.547

ARMC10

0.547

TOP2A

0.532

TOP2B

0.532

RGN

0.520

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARMC10	FAAH2	ENSP00000319412	ENSP00000364035	armadillo repeat containing 10	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	0.547
ARMC10	GPKOW	ENSP00000319412	ENSP00000156109	armadillo repeat containing 10	G patch domain and KOW motifs	0.562
ARMCX3	FAAH2	ENSP00000340672	ENSP00000364035	armadillo repeat containing, X-linked 3	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	0.547
ARMCX3	GPKOW	ENSP00000340672	ENSP00000156109	armadillo repeat containing, X-linked 3	G patch domain and KOW motifs	0.562
EPRS	FAAH2	ENSP00000355890	ENSP00000364035	glutamyl-prolyl-tRNA synthetase	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	0.571
EPRS	PET112	ENSP00000355890	ENSP00000263985	glutamyl-prolyl-tRNA synthetase	PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)	0.675
EPRS	TOP2A	ENSP00000355890	ENSP00000411532	glutamyl-prolyl-tRNA synthetase	topoisomerase (DNA) II alpha 170kDa	0.722
EPRS	TOP2B	ENSP00000355890	ENSP00000396704	glutamyl-prolyl-tRNA synthetase	topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene	0.713
FAAH2	ARMC10	ENSP00000364035	ENSP00000319412	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	armadillo repeat containing 10	0.547
FAAH2	ARMCX3	ENSP00000364035	ENSP00000340672	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	armadillo repeat containing, X-linked 3	0.547
FAAH2	EPRS	ENSP00000364035	ENSP00000355890	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	glutamyl-prolyl-tRNA synthetase	0.571
FAAH2	GPKOW	ENSP00000364035	ENSP00000156109	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	G patch domain and KOW motifs	0.732
FAAH2	PEPD	ENSP00000364035	ENSP00000244137	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	peptidase D	0.612
FAAH2	PET112	ENSP00000364035	ENSP00000263985	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	PET112 homolog (yeast); Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)	0.941
FAAH2	RGN	ENSP00000364035	ENSP00000253303	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	regucalcin (senescence marker protein-30); Gluconolactonase with low activity towards other sugar lactones, including gulonolactone and galactonolactone. Can also hydrolyze diisopropyl phosphorofluoridate and phenylacetate (in vitro). Calcium-binding protein. Modulates Ca(2+) signaling, and Ca(2+)-dependent cellular processes and enzyme activities (By similarity)	0.520
FAAH2	TMEM106C	ENSP00000364035	ENSP00000400471	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	transmembrane protein 106C	0.720
FAAH2	TOP2A	ENSP00000364035	ENSP00000411532	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	topoisomerase (DNA) II alpha 170kDa	0.532
FAAH2	TOP2B	ENSP00000364035	ENSP00000396704	fatty acid amide hydrolase 2; Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates	topoisomerase (DNA) II beta 180kDa; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Indirectly involved in vitamin D- coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR- mediated transrepression of the CYP27B1 gene	0.532
GPKOW	ARMC10	ENSP00000156109	ENSP00000319412	G patch domain and KOW motifs	armadillo repeat containing 10	0.562
GPKOW	ARMCX3	ENSP00000156109	ENSP00000340672	G patch domain and KOW motifs	armadillo repeat containing, X-linked 3	0.562

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