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STRINGSTRING
CST8 CST8 C12orf71 C12orf71 BTN2A1 BTN2A1 FGFR2 FGFR2 LYZL1 LYZL1 EGFLAM EGFLAM TAPBPL TAPBPL SIRPB1 SIRPB1 HSPG2 HSPG2 BTN2A2 BTN2A2 EYS EYS
"LYZL1" - lysozyme-like 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LYZL1lysozyme-like 1 (194 aa)    
Predicted Functional Partners:
TAPBPL
TAP binding protein-like (468 aa)
        score_image       0.888
HSPG2
heparan sulfate proteoglycan 2; Integral component of basement membranes. Component of the glomerular basement membrane (GBM), responsible for the fixed negative electrostatic membrane charge, and which provides a barrier which is both size- and charge-selective. It serves as an attachment substrate for cells. Plays essential roles in vascularization. Critical for normal heart development and for regulating the vascular response to injury. Also required for avascular cartilage development (4391 aa)
        score_image       0.849
FGFR2
fibroblast growth factor receptor 2 (822 aa)
        score_image       0.651
C12orf71
chromosome 12 open reading frame 71 (269 aa)
            score_image   0.586
BTN2A2
butyrophilin, subfamily 2, member A2; Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion (By similarity) (523 aa)
        score_image       0.562
BTN2A1
butyrophilin, subfamily 2, member A1 (527 aa)
        score_image       0.562
SIRPB1
signal-regulatory protein beta 1; Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. Participates also in the recruitment of tyrosine kinase SYK (398 aa)
        score_image       0.562
CST8
cystatin 8 (cystatin-related epididymal specific); Performs a specialized role during sperm development and maturation (142 aa)
            score_image   0.483
EYS
eyes shut homolog (Drosophila) (3144 aa)
        score_image       0.414
EGFLAM
EGF-like, fibronectin type III and laminin G domains (1017 aa)
        score_image       0.414
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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