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KDM2A KDM2A XRN1 XRN1 MEGF6 MEGF6 ZBTB40 ZBTB40 WRAP73 WRAP73 FAM3C FAM3C MTHFSD MTHFSD FOXL1 FOXL1 FLJ42280 FLJ42280 CCDC170 CCDC170 STARD3NL STARD3NL
"ZBTB40" - zinc finger and BTB domain containing 40 in Homo sapiens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
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Edges represent protein-protein associations
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Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
ZBTB40zinc finger and BTB domain containing 40; May be involved in transcriptional regulation (1239 aa)    
Predicted Functional Partners:
WRAP73
WD repeat containing, antisense to TP73 (460 aa)
            score_image   0.813
MEGF6
multiple EGF-like-domains 6 (1541 aa)
      score_image     score_image   0.756
CCDC170
coiled-coil domain containing 170 (715 aa)
            score_image   0.640
STARD3NL
STARD3 N-terminal like (234 aa)
            score_image   0.593
FLJ42280
chromosome 7 open reading frame 76 (128 aa)
            score_image   0.581
MTHFSD
methenyltetrahydrofolate synthetase domain containing (383 aa)
            score_image   0.571
XRN1
5’-3’ exoribonuclease 1; Major 5’-3’ exoribonuclease involved in mRNA decay. Required for the 5’-3’-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS) (1706 aa)
      score_image score_image   score_image   0.543
FAM3C
family with sequence similarity 3, member C; May be involved in retinal laminar formation. Promotes epithelial to mesenchymal transition (227 aa)
            score_image   0.543
FOXL1
forkhead box L1; Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity) (345 aa)
        score_image   score_image   0.526
KDM2A
lysine (K)-specific demethylase 2A; Histone demethylase that specifically demethylates ’Lys- 36’ of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 ’Lys-36’ residue while it has weak or no activity for mono- and tri-methylated H3 ’Lys- 36’. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at [...] (1162 aa)
        score_image   score_image   0.501
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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