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STRINGSTRING
ZBTB43 ZBTB43 ZBTB12 ZBTB12 SPOCK3 SPOCK3 VWA7 VWA7 SPOCK1 SPOCK1 SPOCK2 SPOCK2 COL6A5 COL6A5 GNGT2 GNGT2
"VWA7" - von Willebrand factor A domain containing 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
VWA7von Willebrand factor A domain containing 7 (891 aa)    
Predicted Functional Partners:
ZBTB12
zinc finger and BTB domain containing 12 (459 aa)
            score_image   0.560
COL6A5
collagen, type VI, alpha 5 (2615 aa)
            score_image   0.519
GNGT2
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein- effector interaction (By similarity) (69 aa)
            score_image   0.485
ZBTB43
zinc finger and BTB domain containing 43; May be involved in transcriptional regulation (467 aa)
            score_image   0.483
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3 (436 aa)
      score_image         0.473
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2; May participate in diverse steps of neurogenesis. Binds calcium (424 aa)
      score_image         0.473
SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1; May play a role in cell-cell and cell-matrix interactions. May contribute to various neuronal mechanisms in the central nervous system (439 aa)
      score_image         0.473
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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