AGMAT protein (Homo sapiens) - STRING network view

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Score

AGMAT

agmatine ureohydrolase (agmatinase) (352 aa)

Predicted Functional Partners:

ADC

0.989

SRM

0.980

ODC1

0.965

SNRPA

0.916

SAT1

0.910

SF3B5

0.905

ABP1

0.900

SAT2

0.900

SMS

0.689

SCHIP-1

0.667

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABP1	AGMAT	ENSP00000354193	ENSP00000364986	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	agmatine ureohydrolase (agmatinase)	0.900
ABP1	ODC1	ENSP00000354193	ENSP00000234111	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	ornithine decarboxylase 1	0.901
ABP1	SAT1	ENSP00000354193	ENSP00000368572	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	spermidine/spermine N1-acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity- norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine	0.904
ABP1	SAT2	ENSP00000354193	ENSP00000269298	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	spermidine/spermine N1-acetyltransferase family member 2; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity- norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine	0.900
ABP1	SRM	ENSP00000354193	ENSP00000366156	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	spermidine synthase; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine	0.900
ADC	AGMAT	ENSP00000294517	ENSP00000364986	arginine decarboxylase	agmatine ureohydrolase (agmatinase)	0.989
ADC	SMS	ENSP00000294517	ENSP00000385746	arginine decarboxylase	spermine synthase; Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM)	0.821
ADC	SRM	ENSP00000294517	ENSP00000366156	arginine decarboxylase	spermidine synthase; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine	0.917
AGMAT	ABP1	ENSP00000364986	ENSP00000354193	agmatine ureohydrolase (agmatinase)	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	0.900
AGMAT	ADC	ENSP00000364986	ENSP00000294517	agmatine ureohydrolase (agmatinase)	arginine decarboxylase	0.989
AGMAT	ODC1	ENSP00000364986	ENSP00000234111	agmatine ureohydrolase (agmatinase)	ornithine decarboxylase 1	0.965
AGMAT	SAT1	ENSP00000364986	ENSP00000368572	agmatine ureohydrolase (agmatinase)	spermidine/spermine N1-acetyltransferase 1; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity- norspermidine = spermidine >> spermine > N(1)-acetylspermine > putrescine. This highly regulated enzyme allows a fine attenuation of the intracellular concentration of polyamines. Also involved in the regulation of polyamine transport out of cells. Acts on 1,3-diaminopropane, 1,5-diaminopentane, putrescine, spermidine (forming N(1)- and N(8)-acetylspermidine), spermine, N(1)-acetylspermidine and N(8)-acetylspermidine	0.910
AGMAT	SAT2	ENSP00000364986	ENSP00000269298	agmatine ureohydrolase (agmatinase)	spermidine/spermine N1-acetyltransferase family member 2; Enzyme which catalyzes the acetylation of polyamines. Substrate specificity- norspermidine > spermidine = spermine >> N(1)acetylspermine = putrescine	0.900
AGMAT	SCHIP-1	ENSP00000364986	ENSP00000420182	agmatine ureohydrolase (agmatinase)	IQCJ-SCHIP1 readthrough	0.667
AGMAT	SF3B5	ENSP00000364986	ENSP00000356541	agmatine ureohydrolase (agmatinase)	splicing factor 3b, subunit 5, 10kDa	0.905
AGMAT	SMS	ENSP00000364986	ENSP00000385746	agmatine ureohydrolase (agmatinase)	spermine synthase; Catalyzes the production of spermine from spermidine and decarboxylated S-adenosylmethionine (dcSAM)	0.689
AGMAT	SNRPA	ENSP00000364986	ENSP00000243563	agmatine ureohydrolase (agmatinase)	small nuclear ribonucleoprotein polypeptide A; Binds stem loop II of U1 snRNA. It is the first snRNP to interact with pre-mRNA. This interaction is required for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP. In a snRNP-free form (SF-A) may be involved in coupled pre-mRNA splicing and polyadenylation process. Binds preferentially to the 5’-UGCAC-3’ motif in vitro	0.916
AGMAT	SRM	ENSP00000364986	ENSP00000366156	agmatine ureohydrolase (agmatinase)	spermidine synthase; Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine	0.980
ODC1	ABP1	ENSP00000234111	ENSP00000354193	ornithine decarboxylase 1	amiloride binding protein 1 (amine oxidase (copper-containing)); Catalyzes the degradation of compounds such as putrescine, histamine, spermine, and spermidine, substances involved in allergic and immune responses, cell proliferation, tissue differentiation, tumor formation, and possibly apoptosis. Placental DAO is thought to play a role in the regulation of the female reproductive function	0.901
ODC1	AGMAT	ENSP00000234111	ENSP00000364986	ornithine decarboxylase 1	agmatine ureohydrolase (agmatinase)	0.965

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