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STRINGSTRING
CPA1 CPA1 SERPINA3 SERPINA3 REG1A REG1A SPINK1 SPINK1 CTRC CTRC PLAUR PLAUR HTRA1 HTRA1 STATH STATH RPL14 RPL14 ST13 ST13 UBC UBC
"CTRC" - chymotrypsin C in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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from curated databases
experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
CTRCchymotrypsin C (caldecrin); Has chymotrypsin-type protease activity and hypocalcemic activity (268 aa)    
Predicted Functional Partners:
PLAUR
plasminogen activator, urokinase receptor (335 aa)
          score_image     0.900
SPINK1
serine peptidase inhibitor, Kazal type 1; This is a trypsin inhibitor, its physiological function is to prevent the trypsin-catalyzed premature activation of zymogens within the pancreas (79 aa)
      score_image score_image   score_image   0.872
REG1A
regenerating islet-derived 1 alpha; Might act as an inhibitor of spontaneous calcium carbonate precipitation. May be associated with neuronal sprouting in brain, and with brain and pancreas regeneration (166 aa)
      score_image     score_image   0.822
RPL14
ribosomal protein L14 (215 aa)
            score_image   0.758
HTRA1
HtrA serine peptidase 1; Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits sig [...] (480 aa)
            score_image   0.628
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (423 aa)
score_image       score_image   score_image   0.611
STATH
statherin; Salivary protein that stabilizes saliva supersaturated with calcium salts by inhibiting the precipitation of calcium phosphate salts. It also modulates hydroxyapatite crystal formation on the tooth surface (62 aa)
            score_image   0.608
ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 that has a high affinity for substrate protein. Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity) (369 aa)
        score_image   score_image   0.602
UBC
ubiquitin C (685 aa)
        score_image       0.585
CPA1
carboxypeptidase A1 (pancreatic) (419 aa)
      score_image score_image   score_image   0.582
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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