MYLK2 protein (Homo sapiens) - STRING network view

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MYLK2

myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain (596 aa)

Predicted Functional Partners:

MYL2

0.919

MYH14

0.909

CALM1

0.885

CALML6

0.881

MYL9

0.880

CALML5

0.879

CALML3

0.879

MYLPF

0.873

MYL6

0.863

MYL6B

0.861

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CALM1	MYH14	ENSP00000349467	ENSP00000262269	calmodulin 1 (phosphorylase kinase, delta)	myosin, heavy chain 14, non-muscle	0.695
CALM1	MYLK2	ENSP00000349467	ENSP00000365152	calmodulin 1 (phosphorylase kinase, delta)	myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain	0.885
CALML3	MYH14	ENSP00000315299	ENSP00000262269	calmodulin-like 3; May be similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinities, to cellular substrates	myosin, heavy chain 14, non-muscle	0.696
CALML3	MYLK2	ENSP00000315299	ENSP00000365152	calmodulin-like 3; May be similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinities, to cellular substrates	myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain	0.879
CALML5	MYH14	ENSP00000369689	ENSP00000262269	calmodulin-like 5; Binds calcium. May be involved in terminal differentiation of keratinocytes	myosin, heavy chain 14, non-muscle	0.575
CALML5	MYLK2	ENSP00000369689	ENSP00000365152	calmodulin-like 5; Binds calcium. May be involved in terminal differentiation of keratinocytes	myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain	0.879
CALML6	MYH14	ENSP00000304643	ENSP00000262269	calmodulin-like 6	myosin, heavy chain 14, non-muscle	0.575
CALML6	MYLK2	ENSP00000304643	ENSP00000365152	calmodulin-like 6	myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain	0.881
MYH14	CALM1	ENSP00000262269	ENSP00000349467	myosin, heavy chain 14, non-muscle	calmodulin 1 (phosphorylase kinase, delta)	0.695
MYH14	CALML3	ENSP00000262269	ENSP00000315299	myosin, heavy chain 14, non-muscle	calmodulin-like 3; May be similar to that of authentic calmodulin and may actually compete with calmodulin by binding, with different affinities, to cellular substrates	0.696
MYH14	CALML5	ENSP00000262269	ENSP00000369689	myosin, heavy chain 14, non-muscle	calmodulin-like 5; Binds calcium. May be involved in terminal differentiation of keratinocytes	0.575
MYH14	CALML6	ENSP00000262269	ENSP00000304643	myosin, heavy chain 14, non-muscle	calmodulin-like 6	0.575
MYH14	MYL2	ENSP00000262269	ENSP00000228841	myosin, heavy chain 14, non-muscle	myosin, light chain 2, regulatory, cardiac, slow	0.995
MYH14	MYL6	ENSP00000262269	ENSP00000446714	myosin, heavy chain 14, non-muscle	myosin, light chain 6, alkali, smooth muscle and non-muscle; Regulatory light chain of myosin. Does not bind calcium	0.984
MYH14	MYL6B	ENSP00000262269	ENSP00000207437	myosin, heavy chain 14, non-muscle	myosin, light chain 6B, alkali, smooth muscle and non-muscle; Regulatory light chain of myosin. Does not bind calcium	0.862
MYH14	MYL9	ENSP00000262269	ENSP00000279022	myosin, heavy chain 14, non-muscle	myosin, light chain 9, regulatory; Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion	0.999
MYH14	MYLK2	ENSP00000262269	ENSP00000365152	myosin, heavy chain 14, non-muscle	myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain	0.909
MYH14	MYLPF	ENSP00000262269	ENSP00000325239	myosin, heavy chain 14, non-muscle	myosin light chain, phosphorylatable, fast skeletal muscle	0.949
MYL2	MYH14	ENSP00000228841	ENSP00000262269	myosin, light chain 2, regulatory, cardiac, slow	myosin, heavy chain 14, non-muscle	0.995
MYL2	MYLK2	ENSP00000228841	ENSP00000365152	myosin, light chain 2, regulatory, cardiac, slow	myosin light chain kinase 2; Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N- terminus of a myosin light chain	0.919

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