node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGTPBP1 | ASB5 | ENSP00000365251 | ENSP00000296525 | ATP/GTP binding protein 1 | ankyrin repeat and SOCS box containing 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity) | 0.539 |
AGTPBP1 | ATP6V0D1 | ENSP00000365251 | ENSP00000290949 | ATP/GTP binding protein 1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.567 |
AGTPBP1 | ATP6V0D2 | ENSP00000365251 | ENSP00000285393 | ATP/GTP binding protein 1 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.567 |
AGTPBP1 | CPXM2 | ENSP00000365251 | ENSP00000241305 | ATP/GTP binding protein 1 | carboxypeptidase X (M14 family), member 2; May be involved in cell-cell interactions | 0.585 |
AGTPBP1 | LCORL | ENSP00000365251 | ENSP00000371661 | ATP/GTP binding protein 1 | ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) | 0.475 |
AGTPBP1 | NAA35 | ENSP00000365251 | ENSP00000354972 | ATP/GTP binding protein 1 | N(alpha)-acetyltransferase 35, NatC auxiliary subunit; Regulates proliferation of smooth muscle cells (By similarity). Component of the N-terminal acetyltransferase C (NatC) complex which may catalyze acetylation of N-terminal methionine residues | 0.658 |
AGTPBP1 | PNKP | ENSP00000365251 | ENSP00000323511 | ATP/GTP binding protein 1 | polynucleotide kinase 3’-phosphatase; Plays a key role in the repair of DNA damage, functioning as part of both the non-homologous end-joining (NHEJ) and base excision repair (BER) pathways. Through its two catalytic activities, PNK ensures that DNA termini are compatible with extension and ligation by either removing 3’-phosphates from, or by phosphorylating 5’-hydroxyl groups on, the ribose sugar of the DNA backbone | 0.483 |
AGTPBP1 | POLR2G | ENSP00000365251 | ENSP00000301788 | ATP/GTP binding protein 1 | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | 0.520 |
AGTPBP1 | SMG6 | ENSP00000365251 | ENSP00000263073 | ATP/GTP binding protein 1 | smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans); Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5’- (GTGTGG)(4)GTGT-3’ telomeric DNA, but not to a telomerase RNA template component (TER) | 0.520 |
AGTPBP1 | UBC | ENSP00000365251 | ENSP00000344818 | ATP/GTP binding protein 1 | ubiquitin C | 0.504 |
ASB5 | AGTPBP1 | ENSP00000296525 | ENSP00000365251 | ankyrin repeat and SOCS box containing 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity) | ATP/GTP binding protein 1 | 0.539 |
ASB5 | LCORL | ENSP00000296525 | ENSP00000371661 | ankyrin repeat and SOCS box containing 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity) | ligand dependent nuclear receptor corepressor-like; May act as transcription activator that binds DNA elements with the sequence 5’-CCCTATCGATCGATCTCTACCT-3’. May play a role in spermatogenesis (By similarity) | 0.420 |
ASB5 | POLR2G | ENSP00000296525 | ENSP00000301788 | ankyrin repeat and SOCS box containing 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity) | polymerase (RNA) II (DNA directed) polypeptide G; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB7 is part of a subcomplex with RPB4 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex s [...] | 0.458 |
ASB5 | SMG6 | ENSP00000296525 | ENSP00000263073 | ankyrin repeat and SOCS box containing 5; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. May play a role in the initiation of arteriogenesis (By similarity) | smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans); Component of the telomerase ribonucleoprotein (RNP) complex that is essential for the replication of chromosome termini. May have a general role in telomere regulation. Promotes in vitro the ability of TERT to elongate telomeres. Overexpression induces telomere uncapping, chromosomal end-to-end fusions (telomeric DNA persists at the fusion points) and did not perturb TRF2 telomeric localization. Binds to the single-stranded 5’- (GTGTGG)(4)GTGT-3’ telomeric DNA, but not to a telomerase RNA template component (TER) | 0.527 |
ATP6V0D1 | AGTPBP1 | ENSP00000290949 | ENSP00000365251 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | ATP/GTP binding protein 1 | 0.567 |
ATP6V0D1 | ATP6V0D2 | ENSP00000290949 | ENSP00000285393 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.901 |
ATP6V0D1 | UBC | ENSP00000290949 | ENSP00000344818 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | ubiquitin C | 0.946 |
ATP6V0D2 | AGTPBP1 | ENSP00000285393 | ENSP00000365251 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | ATP/GTP binding protein 1 | 0.567 |
ATP6V0D2 | ATP6V0D1 | ENSP00000285393 | ENSP00000290949 | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.901 |
CPXM2 | AGTPBP1 | ENSP00000241305 | ENSP00000365251 | carboxypeptidase X (M14 family), member 2; May be involved in cell-cell interactions | ATP/GTP binding protein 1 | 0.585 |