Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACAN | IDH3A | ENSP00000387356 | ENSP00000299518 | aggrecan; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region | isocitrate dehydrogenase 3 (NAD+) alpha | 0.605 |
ACAN | KIAA1217 | ENSP00000387356 | ENSP00000365637 | aggrecan; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region | KIAA1217 | 0.680 |
EXOSC5 | KIAA1217 | ENSP00000221233 | ENSP00000365637 | exosome component 5; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | KIAA1217 | 0.574 |
FHL2 | KIAA1217 | ENSP00000322909 | ENSP00000365637 | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | KIAA1217 | 0.600 |
FXR2 | KIAA1217 | ENSP00000250113 | ENSP00000365637 | fragile X mental retardation, autosomal homolog 2; RNA-binding protein | KIAA1217 | 0.653 |
IDH2 | IDH3A | ENSP00000331897 | ENSP00000299518 | isocitrate dehydrogenase 2 (NADP+), mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex | isocitrate dehydrogenase 3 (NAD+) alpha | 0.992 |
IDH2 | KIAA1217 | ENSP00000331897 | ENSP00000365637 | isocitrate dehydrogenase 2 (NADP+), mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex | KIAA1217 | 0.668 |
IDH3A | ACAN | ENSP00000299518 | ENSP00000387356 | isocitrate dehydrogenase 3 (NAD+) alpha | aggrecan; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region | 0.605 |
IDH3A | IDH2 | ENSP00000299518 | ENSP00000331897 | isocitrate dehydrogenase 3 (NAD+) alpha | isocitrate dehydrogenase 2 (NADP+), mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex | 0.992 |
IDH3A | KIAA1217 | ENSP00000299518 | ENSP00000365637 | isocitrate dehydrogenase 3 (NAD+) alpha | KIAA1217 | 0.759 |
KIAA0528 | KIAA1217 | ENSP00000334229 | ENSP00000365637 | KIAA0528; Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM | KIAA1217 | 0.683 |
KIAA1217 | ACAN | ENSP00000365637 | ENSP00000387356 | KIAA1217 | aggrecan; This proteoglycan is a major component of extracellular matrix of cartilagenous tissues. A major function of this protein is to resist compression in cartilage. It binds avidly to hyaluronic acid via an N-terminal globular region | 0.680 |
KIAA1217 | EXOSC5 | ENSP00000365637 | ENSP00000221233 | KIAA1217 | exosome component 5; Non-catalytic component of the RNA exosome complex which has 3’->5’ exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding ’pervasive’ transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The R [...] | 0.574 |
KIAA1217 | FHL2 | ENSP00000365637 | ENSP00000322909 | KIAA1217 | four and a half LIM domains 2; May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation | 0.600 |
KIAA1217 | FXR2 | ENSP00000365637 | ENSP00000250113 | KIAA1217 | fragile X mental retardation, autosomal homolog 2; RNA-binding protein | 0.653 |
KIAA1217 | IDH2 | ENSP00000365637 | ENSP00000331897 | KIAA1217 | isocitrate dehydrogenase 2 (NADP+), mitochondrial; Plays a role in intermediary metabolism and energy production. It may tightly associate or interact with the pyruvate dehydrogenase complex | 0.668 |
KIAA1217 | IDH3A | ENSP00000365637 | ENSP00000299518 | KIAA1217 | isocitrate dehydrogenase 3 (NAD+) alpha | 0.759 |
KIAA1217 | KIAA0528 | ENSP00000365637 | ENSP00000334229 | KIAA1217 | KIAA0528; Required for insulin-stimulated glucose transport and glucose transporter SLC2A4/GLUT4 translocation from intracellular glucose storage vesicle (GSV) to the plasma membrane (PM) in adipocytes. Binds phospholipid membranes in a calcium-dependent manner and is necessary for the optimal membrane fusion between SLC2A4/GLUT4 GSV and the PM | 0.683 |
KIAA1217 | LASP1 | ENSP00000365637 | ENSP00000325240 | KIAA1217 | LIM and SH3 protein 1; Plays an important role in the regulation of dynamic actin-based, cytoskeletal activities. Agonist-dependent changes in LASP1 phosphorylation may also serve to regulate actin-associated ion transport activities, not only in the parietal cell but also in certain other F-actin-rich secretory epithelial cell types (By similarity) | 0.560 |
KIAA1217 | PLXDC1 | ENSP00000365637 | ENSP00000323927 | KIAA1217 | plexin domain containing 1; Plays a critical role in endothelial cell capillary morphogenesis (By similarity) | 0.576 |
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