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ACAT2 ACAT2 KIAA1598 KIAA1598 FH FH PSAT1 PSAT1 TUBB6 TUBB6 STAT6 STAT6 UBC UBC CTBP2 CTBP2 PHGDH PHGDH CTBP1 CTBP1 PSPH PSPH
"PSAT1" - phosphoserine aminotransferase 1 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
PSAT1phosphoserine aminotransferase 1; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity) (370 aa)    
Predicted Functional Partners:
PHGDH
phosphoglycerate dehydrogenase (533 aa)
score_image     score_image   score_image score_image   0.996
UBC
ubiquitin C (685 aa)
        score_image       0.990
PSPH
phosphoserine phosphatase; Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme intermediates (225 aa)
score_image     score_image   score_image score_image   0.982
KIAA1598
KIAA1598 (631 aa)
        score_image       0.913
TUBB6
tubulin, beta 6 class V; Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity) (446 aa)
        score_image       0.896
STAT6
signal transducer and activator of transcription 6, interleukin-4 induced; Carries out a dual function- signal transduction and activation of transcription. Involved in interleukin-4 signalling (847 aa)
        score_image       0.880
CTBP2
C-terminal binding protein 2; Corepressor targeting diverse transcription regulators. Functions in brown adipose tissue (BAT) differentiation (By similarity) (985 aa)
score_image     score_image     score_image   0.771
CTBP1
C-terminal binding protein 1; Involved in controlling the equilibrium between tubular and stacked structures in the Golgi complex. Functions in brown adipose tissue (BAT) differentiation. Corepressor targeting diverse transcription regulators such as GLIS2. Has dehydrogenase activity (440 aa)
score_image     score_image     score_image   0.771
ACAT2
acetyl-CoA acetyltransferase 2 (397 aa)
      score_image score_image   score_image   0.681
FH
fumarate hydratase; Also acts as a tumor suppressor (510 aa)
        score_image   score_image   0.680
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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