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STRINGSTRING
UBE4B UBE4B PEX14 PEX14 C1orf127 C1orf127 RBP7 RBP7 NEURL1B NEURL1B NEURL NEURL ANGPTL7 ANGPTL7 RALGPS2 RALGPS2 LDLRAD3 LDLRAD3 MYOC MYOC ZNF263 ZNF263
"ANGPTL7" - angiopoietin-like 7 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANGPTL7angiopoietin-like 7 (346 aa)    
Predicted Functional Partners:
C1orf127
chromosome 1 open reading frame 127 (823 aa)
            score_image   0.653
LDLRAD3
low density lipoprotein receptor class A domain containing 3; May influence APP processing, resulting in a decrease in sAPP-alpha production and increased amyloidogenic P3 peptide production (By similarity) (345 aa)
            score_image   0.623
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2; Guanine nucleotide exchange factor for the small GTPase RALA. May be involved in cytoskeletal organization. May also be involved in the stimulation of transcription in a Ras-independent fashion (By similarity) (583 aa)
            score_image   0.597
MYOC
myocilin, trabecular meshwork inducible glucocorticoid response; May participate in the obstruction of fluid outflow in the trabecular meshwork (504 aa)
      score_image     score_image   0.580
NEURL1B
neuralized homolog 1B (Drosophila); E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands (555 aa)
            score_image   0.560
NEURL
neuralized homolog (Drosophila); May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) (574 aa)
            score_image   0.560
RBP7
retinol binding protein 7, cellular; Intracellular transport of retinol (134 aa)
            score_image   0.534
PEX14
peroxisomal biogenesis factor 14; Component of the peroxisomal translocation machinery with PEX13 and PEX17. Interacts with both the PTS1 and PTS2 receptors. Binds directly to PEX17 (377 aa)
            score_image   0.530
ZNF263
zinc finger protein 263; Might play an important role in basic cellular processes as a transcriptional repressor (683 aa)
            score_image   0.523
UBE4B
ubiquitination factor E4B; Binds to the ubiquitin moieties of preformed conjugates and catalyzes ubiquitin chain assembly in conjunction with E1, E2, and E3 (By similarity) (1302 aa)
            score_image   0.505
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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