node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LONRF3 | TBC1D8 | ENSP00000360690 | ENSP00000366036 | LON peptidase N-terminal domain and ring finger 3 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.583 |
MFSD9 | PDCL3 | ENSP00000258436 | ENSP00000264254 | major facilitator superfamily domain containing 9 | phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination | 0.615 |
MFSD9 | TBC1D8 | ENSP00000258436 | ENSP00000366036 | major facilitator superfamily domain containing 9 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.625 |
PDCL3 | MFSD9 | ENSP00000264254 | ENSP00000258436 | phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination | major facilitator superfamily domain containing 9 | 0.615 |
PDCL3 | TBC1D8 | ENSP00000264254 | ENSP00000366036 | phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.601 |
RAB34 | TBC1D8 | ENSP00000410403 | ENSP00000366036 | RAB34, member RAS oncogene family; Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.578 |
RAB36 | TBC1D8 | ENSP00000263116 | ENSP00000366036 | RAB36, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.578 |
RAB41 | TBC1D8 | ENSP00000276066 | ENSP00000366036 | RAB41, member RAS oncogene family | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.582 |
RAB6A | TBC1D8 | ENSP00000311449 | ENSP00000366036 | RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.582 |
RAB6B | TBC1D8 | ENSP00000285208 | ENSP00000366036 | RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.582 |
RAB6C | TBC1D8 | ENSP00000387307 | ENSP00000366036 | RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | 0.582 |
TBC1D8 | LONRF3 | ENSP00000366036 | ENSP00000360690 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | LON peptidase N-terminal domain and ring finger 3 | 0.583 |
TBC1D8 | MFSD9 | ENSP00000366036 | ENSP00000258436 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | major facilitator superfamily domain containing 9 | 0.625 |
TBC1D8 | PDCL3 | ENSP00000366036 | ENSP00000264254 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | phosducin-like 3; Modulates the activation of caspases during apoptosis. Is a substrate for Orgyia pseudotsugata multicapsid polyhedrosis virus (OpMNPV) IAP-mediated ubiquitination | 0.601 |
TBC1D8 | RAB34 | ENSP00000366036 | ENSP00000410403 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | RAB34, member RAS oncogene family; Protein transport. Involved in the redistribution of lysosomes to the peri-Golgi region (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. Plays a role in the fusion of phagosomes with lysosomes | 0.578 |
TBC1D8 | RAB36 | ENSP00000366036 | ENSP00000263116 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | RAB36, member RAS oncogene family; Protein transport. Probably involved in vesicular traffic (By similarity) | 0.578 |
TBC1D8 | RAB41 | ENSP00000366036 | ENSP00000276066 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | RAB41, member RAS oncogene family | 0.582 |
TBC1D8 | RAB6A | ENSP00000366036 | ENSP00000311449 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | RAB6A, member RAS oncogene family; Protein transport. Regulator of membrane traffic from the Golgi apparatus towards the endoplasmic reticulum (ER). Has a low GTPase activity | 0.582 |
TBC1D8 | RAB6B | ENSP00000366036 | ENSP00000285208 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | RAB6B, member RAS oncogene family; Seems to have a role in retrograde membrane traffic at the level of the Golgi complex. May function in retrograde transport in neuronal cells | 0.582 |
TBC1D8 | RAB6C | ENSP00000366036 | ENSP00000387307 | TBC1 domain family, member 8 (with GRAM domain); May act as a GTPase-activating protein for Rab family protein(s) | RAB6C, member RAS oncogene family; May be involved in the regulation of centrosome duplication and cell cycle progression | 0.582 |