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STRINGSTRING
CNTD1 CNTD1 FAM134C FAM134C ABCB10 ABCB10 SLC25A35 SLC25A35 SLC25A39 SLC25A39 SFN SFN RUNDC3A RUNDC3A YWHAG YWHAG GRN GRN TARDBP TARDBP TMEM14C TMEM14C
"SLC25A39" - solute carrier family 25, member 39 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
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Experiments
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[Homology]
Score
SLC25A39solute carrier family 25, member 39; Required for normal heme biosynthesis (By similarity) (359 aa)    
Predicted Functional Partners:
RUNDC3A
RUN domain containing 3A; May act as an effector of RAP2A in neuronal cells (By similarity) (446 aa)
            score_image   0.766
CNTD1
cyclin N-terminal domain containing 1 (330 aa)
            score_image   0.674
FAM134C
family with sequence similarity 134, member C (466 aa)
            score_image   0.667
GRN
granulin (593 aa)
            score_image   0.606
SFN
stratifin; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway (By similarity) (248 aa)
        score_image   score_image   0.579
TMEM14C
transmembrane protein 14C; Required for normal heme biosynthesis (By similarity) (112 aa)
            score_image   0.575
YWHAG
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide; Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner (247 aa)
        score_image       0.571
TARDBP
TAR DNA binding protein (414 aa)
            score_image   0.562
SLC25A35
solute carrier family 25, member 35 (295 aa)
            score_image   0.553
ABCB10
ATP-binding cassette, sub-family B (MDR/TAP), member 10; May mediate critical mitochondrial transport functions related to heme biosynthesis (By similarity) (738 aa)
            score_image   0.549
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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