Export your current network:
... as a bitmap image:
file format is 'PNG': portable network graphic
... as a high-resolution bitmap:
same PNG format, but resolution at 400 dpi
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as simple tabular text output:
TSV: tab separated values - can be opened in Excel
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and annotated functions of the network proteins
Browse interactions in tabular form:
node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NADK | NADSYN1 | ENSP00000340925 | ENSP00000326424 | NAD kinase | NAD synthetase 1 | 0.900 |
NADK | NMNAT1 | ENSP00000340925 | ENSP00000366410 | NAD kinase | nicotinamide nucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails [...] | 0.969 |
NADK | NNT | ENSP00000340925 | ENSP00000264663 | NAD kinase | nicotinamide nucleotide transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland | 0.867 |
NADK | QPRT | ENSP00000340925 | ENSP00000378782 | NAD kinase | quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA) | 0.407 |
NADSYN1 | NADK | ENSP00000326424 | ENSP00000340925 | NAD synthetase 1 | NAD kinase | 0.900 |
NADSYN1 | NAMPTL | ENSP00000326424 | ENSP00000407952 | NAD synthetase 1 | nicotinamide phosphoribosyltransferase-like | 0.838 |
NADSYN1 | NAPRT1 | ENSP00000326424 | ENSP00000401508 | NAD synthetase 1 | nicotinate phosphoribosyltransferase domain containing 1; Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells | 0.863 |
NADSYN1 | NMNAT1 | ENSP00000326424 | ENSP00000366410 | NAD synthetase 1 | nicotinamide nucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails [...] | 0.984 |
NADSYN1 | NMRK2 | ENSP00000326424 | ENSP00000168977 | NAD synthetase 1 | nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis | 0.450 |
NADSYN1 | NNT | ENSP00000326424 | ENSP00000264663 | NAD synthetase 1 | nicotinamide nucleotide transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland | 0.957 |
NADSYN1 | QPRT | ENSP00000326424 | ENSP00000378782 | NAD synthetase 1 | quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA) | 0.708 |
NAMPTL | NADSYN1 | ENSP00000407952 | ENSP00000326424 | nicotinamide phosphoribosyltransferase-like | NAD synthetase 1 | 0.838 |
NAMPTL | NMNAT1 | ENSP00000407952 | ENSP00000366410 | nicotinamide phosphoribosyltransferase-like | nicotinamide nucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails [...] | 0.948 |
NAMPTL | NMRK1 | ENSP00000407952 | ENSP00000354387 | nicotinamide phosphoribosyltransferase-like | nicotinamide riboside kinase 1; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). The enzyme also phosphorylates the antitumor drugs tiazofurin and 3- deazaguanosine | 0.931 |
NAMPTL | NMRK2 | ENSP00000407952 | ENSP00000168977 | nicotinamide phosphoribosyltransferase-like | nicotinamide riboside kinase 2; Catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). Reduces laminin matrix deposition and cell adhesion to laminin, but not to fibronectin. Involved in the regulation of PXN at the protein level and of PXN tyrosine phosphorylation. May play a role in the regulation of terminal myogenesis | 0.931 |
NAMPTL | NNT | ENSP00000407952 | ENSP00000264663 | nicotinamide phosphoribosyltransferase-like | nicotinamide nucleotide transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane. May play a role in reactive oxygen species (ROS) detoxification in the adrenal gland | 0.546 |
NAMPTL | NT5E | ENSP00000407952 | ENSP00000257770 | nicotinamide phosphoribosyltransferase-like | 5’-nucleotidase, ecto (CD73); Hydrolyzes extracellular nucleotides into membrane permeable nucleosides. Exhibits AMP-, NAD-, and NMN-nucleosidase activities | 0.902 |
NAMPTL | QPRT | ENSP00000407952 | ENSP00000378782 | nicotinamide phosphoribosyltransferase-like | quinolinate phosphoribosyltransferase; Involved in the catabolism of quinolinic acid (QA) | 0.706 |
NAPRT1 | NADSYN1 | ENSP00000401508 | ENSP00000326424 | nicotinate phosphoribosyltransferase domain containing 1; Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells | NAD synthetase 1 | 0.863 |
NAPRT1 | NMNAT1 | ENSP00000401508 | ENSP00000366410 | nicotinate phosphoribosyltransferase domain containing 1; Catalyzes the conversion of nicotinic acid (NA) to NA mononucleotide (NaMN). Essential for NA to increase cellular NAD levels and prevent oxidative stress of the cells | nicotinamide nucleotide adenylyltransferase 1; Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails [...] | 0.967 |
page 1 of 4