ARL5B protein (Homo sapiens) - STRING network view

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ARL5B

ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP (179 aa)

Predicted Functional Partners:

UBC

0.778

GBF1

0.664

ENSG00000262633

0.636

GOSR2

0.636

ACLY

0.621

ARFGAP3

0.621

ARFGAP2

0.615

MGAM

0.606

ENSG00000267261

0.580

MON2

0.566

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACLY	ARL5B	ENSP00000253792	ENSP00000366487	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	0.621
ACLY	UBC	ENSP00000253792	ENSP00000344818	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	ubiquitin C	0.687
ARFGAP2	ARL5B	ENSP00000434442	ENSP00000366487	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	0.615
ARFGAP2	ENSG00000262633	ENSP00000434442	ENSP00000461460	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	Golgi SNAP receptor complex member 2; Uncharacterized protein	0.767
ARFGAP2	GBF1	ENSP00000434442	ENSP00000359000	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	golgi brefeldin A resistant guanine nucleotide exchange factor 1; Promotes guanine-nucleotide exchange on ARF5. Promotes the activation of ARF5 through replacement of GDP with GTP (By similarity)	0.459
ARFGAP2	GOSR2	ENSP00000434442	ENSP00000225567	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network	0.767
ARFGAP2	MON2	ENSP00000434442	ENSP00000377252	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	MON2 homolog (S. cerevisiae); May be required for traffic between late Golgi and early endosomes (By similarity)	0.478
ARFGAP2	UBC	ENSP00000434442	ENSP00000344818	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	ubiquitin C	0.678
ARFGAP3	ARL5B	ENSP00000263245	ENSP00000366487	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	0.621
ARFGAP3	ENSG00000262633	ENSP00000263245	ENSP00000461460	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	Golgi SNAP receptor complex member 2; Uncharacterized protein	0.772
ARFGAP3	GBF1	ENSP00000263245	ENSP00000359000	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	golgi brefeldin A resistant guanine nucleotide exchange factor 1; Promotes guanine-nucleotide exchange on ARF5. Promotes the activation of ARF5 through replacement of GDP with GTP (By similarity)	0.460
ARFGAP3	GOSR2	ENSP00000263245	ENSP00000225567	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial- Golgi to the trans-Golgi network	0.775
ARFGAP3	MON2	ENSP00000263245	ENSP00000377252	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	MON2 homolog (S. cerevisiae); May be required for traffic between late Golgi and early endosomes (By similarity)	0.478
ARFGAP3	UBC	ENSP00000263245	ENSP00000344818	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	ubiquitin C	0.763
ARL5B	ACLY	ENSP00000366487	ENSP00000253792	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	ATP citrate lyase; ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine	0.621
ARL5B	ARFGAP2	ENSP00000366487	ENSP00000434442	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	ADP-ribosylation factor GTPase activating protein 2; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	0.615
ARL5B	ARFGAP3	ENSP00000366487	ENSP00000263245	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	ADP-ribosylation factor GTPase activating protein 3; GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes	0.621
ARL5B	ENSG00000262633	ENSP00000366487	ENSP00000461460	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	Golgi SNAP receptor complex member 2; Uncharacterized protein	0.636
ARL5B	ENSG00000267261	ENSP00000366487	ENSP00000468367	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	Ras-related protein Rab-5C	0.580
ARL5B	GBF1	ENSP00000366487	ENSP00000359000	ADP-ribosylation factor-like 5B; Binds and exchanges GTP and GDP	golgi brefeldin A resistant guanine nucleotide exchange factor 1; Promotes guanine-nucleotide exchange on ARF5. Promotes the activation of ARF5 through replacement of GDP with GTP (By similarity)	0.664

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