node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DNAJC11 | GRPEL1 | ENSP00000366800 | ENSP00000264954 | DnaJ (Hsp40) homolog, subfamily C, member 11 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | 0.835 |
DNAJC11 | GRPEL2 | ENSP00000366800 | ENSP00000329558 | DnaJ (Hsp40) homolog, subfamily C, member 11 | GrpE-like 2, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity) | 0.835 |
DNAJC11 | HSPA14 | ENSP00000366800 | ENSP00000367623 | DnaJ (Hsp40) homolog, subfamily C, member 11 | heat shock 70kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity | 0.776 |
DNAJC11 | HSPA1A | ENSP00000366800 | ENSP00000364802 | DnaJ (Hsp40) homolog, subfamily C, member 11 | heat shock 70kDa protein 1A | 0.776 |
DNAJC11 | HSPA1B | ENSP00000366800 | ENSP00000364801 | DnaJ (Hsp40) homolog, subfamily C, member 11 | heat shock 70kDa protein 1B | 0.776 |
DNAJC11 | HSPA1L | ENSP00000366800 | ENSP00000364805 | DnaJ (Hsp40) homolog, subfamily C, member 11 | heat shock 70kDa protein 1-like | 0.776 |
DNAJC11 | HSPA9 | ENSP00000366800 | ENSP00000297185 | DnaJ (Hsp40) homolog, subfamily C, member 11 | heat shock 70kDa protein 9 (mortalin) | 0.804 |
DNAJC11 | HYOU1 | ENSP00000366800 | ENSP00000384144 | DnaJ (Hsp40) homolog, subfamily C, member 11 | hypoxia up-regulated 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding | 0.776 |
DNAJC11 | MINOS1 | ENSP00000366800 | ENSP00000325562 | DnaJ (Hsp40) homolog, subfamily C, member 11 | mitochondrial inner membrane organizing system 1; May play a role in mitochondrial architecture (By similarity) | 0.875 |
DNAJC11 | UBC | ENSP00000366800 | ENSP00000344818 | DnaJ (Hsp40) homolog, subfamily C, member 11 | ubiquitin C | 0.871 |
GRPEL1 | DNAJC11 | ENSP00000264954 | ENSP00000366800 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | DnaJ (Hsp40) homolog, subfamily C, member 11 | 0.835 |
GRPEL1 | GRPEL2 | ENSP00000264954 | ENSP00000329558 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | GrpE-like 2, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity) | 0.908 |
GRPEL1 | HSPA14 | ENSP00000264954 | ENSP00000367623 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | heat shock 70kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity | 0.987 |
GRPEL1 | HSPA1A | ENSP00000264954 | ENSP00000364802 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | heat shock 70kDa protein 1A | 0.993 |
GRPEL1 | HSPA1B | ENSP00000264954 | ENSP00000364801 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | heat shock 70kDa protein 1B | 0.988 |
GRPEL1 | HSPA1L | ENSP00000264954 | ENSP00000364805 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | heat shock 70kDa protein 1-like | 0.987 |
GRPEL1 | HSPA9 | ENSP00000264954 | ENSP00000297185 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | heat shock 70kDa protein 9 (mortalin) | 0.999 |
GRPEL1 | HYOU1 | ENSP00000264954 | ENSP00000384144 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | hypoxia up-regulated 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding | 0.986 |
GRPEL1 | UBC | ENSP00000264954 | ENSP00000344818 | GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins | ubiquitin C | 0.483 |
GRPEL2 | DNAJC11 | ENSP00000329558 | ENSP00000366800 | GrpE-like 2, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity) | DnaJ (Hsp40) homolog, subfamily C, member 11 | 0.835 |