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STRINGSTRING
HYOU1 HYOU1 MINOS1 MINOS1 DNAJC11 DNAJC11 HSPA14 HSPA14 HSPA1A HSPA1A GRPEL1 GRPEL1 HSPA9 HSPA9 HSPA1L HSPA1L GRPEL2 GRPEL2 HSPA1B HSPA1B UBC UBC
"DNAJC11" - DnaJ in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DNAJC11DnaJ (Hsp40) homolog, subfamily C, member 11 (559 aa)    
Predicted Functional Partners:
MINOS1
mitochondrial inner membrane organizing system 1; May play a role in mitochondrial architecture (By similarity) (78 aa)
        score_image   score_image   0.875
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.871
GRPEL2
GrpE-like 2, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins. Stimulates ATPase activity of mt-HSP70. May also serve to modulate the interconversion of oligomeric (inactive) and monomeric (active) forms of mt-HSP70 (By similarity) (225 aa)
score_image     score_image score_image   score_image   0.835
GRPEL1
GrpE-like 1, mitochondrial (E. coli); Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (217 aa)
score_image     score_image score_image   score_image   0.835
HSPA9
heat shock 70kDa protein 9 (mortalin) (679 aa)
score_image     score_image score_image   score_image   0.804
HYOU1
hypoxia up-regulated 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding (999 aa)
score_image     score_image score_image   score_image   0.776
HSPA14
heat shock 70kDa protein 14; Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity (509 aa)
score_image     score_image score_image   score_image   0.776
HSPA1L
heat shock 70kDa protein 1-like (641 aa)
score_image     score_image score_image   score_image   0.776
HSPA1A
heat shock 70kDa protein 1A (641 aa)
score_image     score_image score_image   score_image   0.776
HSPA1B
heat shock 70kDa protein 1B (641 aa)
score_image     score_image score_image   score_image   0.776
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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