node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATXN2 | DDX6 | ENSP00000366843 | ENSP00000264018 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | DEAD (Asp-Glu-Ala-Asp) box helicase 6; In the process of mRNA degradation, may play a role in mRNA decapping | 0.957 |
ATXN2 | FUS | ENSP00000366843 | ENSP00000254108 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | fused in sarcoma; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity | 0.896 |
ATXN2 | LSM12 | ENSP00000366843 | ENSP00000293406 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | LSM12 homolog (S. cerevisiae) | 0.914 |
ATXN2 | PABPC1 | ENSP00000366843 | ENSP00000313007 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | poly(A) binding protein, cytoplasmic 1; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre- mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability [...] | 0.998 |
ATXN2 | RBFOX1 | ENSP00000366843 | ENSP00000309117 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | RNA binding protein, fox-1 homolog (C. elegans) 1; RNA-binding protein that regulates alternative splicing events by binding to 5’-UGCAUGU-3’ elements. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis | 0.991 |
ATXN2 | RBFOX2 | ENSP00000366843 | ENSP00000413035 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | RNA binding protein, fox-1 homolog (C. elegans) 2; RNA-binding protein that regulates alternative splicing events (By similarity) | 0.958 |
ATXN2 | SH3GL2 | ENSP00000366843 | ENSP00000369981 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | SH3-domain GRB2-like 2; Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature | 0.911 |
ATXN2 | SH3GL3 | ENSP00000366843 | ENSP00000391372 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | SH3-domain GRB2-like 3; Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity) | 0.912 |
ATXN2 | TARDBP | ENSP00000366843 | ENSP00000240185 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | TAR DNA binding protein | 0.984 |
ATXN2 | UBC | ENSP00000366843 | ENSP00000344818 | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | ubiquitin C | 0.929 |
DDX6 | ATXN2 | ENSP00000264018 | ENSP00000366843 | DEAD (Asp-Glu-Ala-Asp) box helicase 6; In the process of mRNA degradation, may play a role in mRNA decapping | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | 0.957 |
DDX6 | LSM12 | ENSP00000264018 | ENSP00000293406 | DEAD (Asp-Glu-Ala-Asp) box helicase 6; In the process of mRNA degradation, may play a role in mRNA decapping | LSM12 homolog (S. cerevisiae) | 0.706 |
DDX6 | PABPC1 | ENSP00000264018 | ENSP00000313007 | DEAD (Asp-Glu-Ala-Asp) box helicase 6; In the process of mRNA degradation, may play a role in mRNA decapping | poly(A) binding protein, cytoplasmic 1; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre- mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability [...] | 0.780 |
DDX6 | UBC | ENSP00000264018 | ENSP00000344818 | DEAD (Asp-Glu-Ala-Asp) box helicase 6; In the process of mRNA degradation, may play a role in mRNA decapping | ubiquitin C | 0.582 |
FUS | ATXN2 | ENSP00000254108 | ENSP00000366843 | fused in sarcoma; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | 0.896 |
FUS | TARDBP | ENSP00000254108 | ENSP00000240185 | fused in sarcoma; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity | TAR DNA binding protein | 0.948 |
FUS | UBC | ENSP00000254108 | ENSP00000344818 | fused in sarcoma; Binds both single-stranded and double-stranded DNA and promotes ATP-independent annealing of complementary single- stranded DNAs and D-loop formation in superhelical double-stranded DNA. May play a role in maintenance of genomic integrity | ubiquitin C | 0.925 |
LSM12 | ATXN2 | ENSP00000293406 | ENSP00000366843 | LSM12 homolog (S. cerevisiae) | ataxin 2; Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane | 0.914 |
LSM12 | DDX6 | ENSP00000293406 | ENSP00000264018 | LSM12 homolog (S. cerevisiae) | DEAD (Asp-Glu-Ala-Asp) box helicase 6; In the process of mRNA degradation, may play a role in mRNA decapping | 0.706 |
LSM12 | PABPC1 | ENSP00000293406 | ENSP00000313007 | LSM12 homolog (S. cerevisiae) | poly(A) binding protein, cytoplasmic 1; Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism such as pre- mRNA splicing. Its function in translational initiation regulation can either be enhanced by PAIP1 or repressed by PAIP2. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo. Involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability [...] | 0.551 |