GPR20 protein (Homo sapiens) - STRING network view

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Size

small nodes:
protein of unknown 3D structure

large nodes:
some 3D structure is known or predicted

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

GPR20

G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP (358 aa)

Predicted Functional Partners:

GPR22

0.889

GPR21

0.883

SST

0.481

GPR26

0.413

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but resolution at 400 dpi

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as simple tabular text output:

download

TSV: tab separated values - can be opened in Excel

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
GPR20	GPR21	ENSP00000366970	ENSP00000362746	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	G protein-coupled receptor 21; Orphan receptor	0.883
GPR20	GPR22	ENSP00000366970	ENSP00000302676	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	G protein-coupled receptor 22; Orphan receptor	0.889
GPR20	GPR26	ENSP00000366970	ENSP00000284674	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	G protein-coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP	0.413
GPR20	SST	ENSP00000366970	ENSP00000287641	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	somatostatin; Somatostatin inhibits the release of somatotropin	0.481
GPR21	GPR20	ENSP00000362746	ENSP00000366970	G protein-coupled receptor 21; Orphan receptor	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	0.883
GPR21	GPR22	ENSP00000362746	ENSP00000302676	G protein-coupled receptor 21; Orphan receptor	G protein-coupled receptor 22; Orphan receptor	0.860
GPR21	GPR26	ENSP00000362746	ENSP00000284674	G protein-coupled receptor 21; Orphan receptor	G protein-coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP	0.550
GPR21	SST	ENSP00000362746	ENSP00000287641	G protein-coupled receptor 21; Orphan receptor	somatostatin; Somatostatin inhibits the release of somatotropin	0.440
GPR22	GPR20	ENSP00000302676	ENSP00000366970	G protein-coupled receptor 22; Orphan receptor	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	0.889
GPR22	GPR21	ENSP00000302676	ENSP00000362746	G protein-coupled receptor 22; Orphan receptor	G protein-coupled receptor 21; Orphan receptor	0.860
GPR22	SST	ENSP00000302676	ENSP00000287641	G protein-coupled receptor 22; Orphan receptor	somatostatin; Somatostatin inhibits the release of somatotropin	0.481
GPR26	GPR20	ENSP00000284674	ENSP00000366970	G protein-coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	0.413
GPR26	GPR21	ENSP00000284674	ENSP00000362746	G protein-coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP	G protein-coupled receptor 21; Orphan receptor	0.550
SST	GPR20	ENSP00000287641	ENSP00000366970	somatostatin; Somatostatin inhibits the release of somatotropin	G protein-coupled receptor 20; Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP	0.481
SST	GPR21	ENSP00000287641	ENSP00000362746	somatostatin; Somatostatin inhibits the release of somatotropin	G protein-coupled receptor 21; Orphan receptor	0.440
SST	GPR22	ENSP00000287641	ENSP00000302676	somatostatin; Somatostatin inhibits the release of somatotropin	G protein-coupled receptor 22; Orphan receptor	0.481

Textmining

Cooccurrence

Experiments

Neighborhood

Databases

Fusion

Coexpression

© STRING Consortium 2017

Credits

Access

Info

About