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STRINGSTRING
RIC8A RIC8A GPSM2 GPSM2 FBXO10 FBXO10 FRMPD1 FRMPD1 TTC29 TTC29 USP9X USP9X MACF1 MACF1
"FRMPD1" - FERM and PDZ domain containing 1 in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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some 3D structure is known or predicted
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query proteins and first shell of interactors
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white nodes:
second shell of interactors
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Known Interactions
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experiment edge
experimentally determined
Predicted Interactions
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fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
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textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
FRMPD1FERM and PDZ domain containing 1; Stabilizes membrane-bound GPSM1, and thereby promotes its interaction with GNAI1 (1578 aa)    
Predicted Functional Partners:
FBXO10
F-box protein 10; Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex (By similarity) (956 aa)
            score_image   0.695
TTC29
tetratricopeptide repeat domain 29 (475 aa)
            score_image   0.629
GPSM2
G-protein signaling modulator 2; Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions (684 aa)
            score_image   0.456
MACF1
microtubule-actin crosslinking factor 1 (5430 aa)
            score_image   0.451
RIC8A
resistance to inhibitors of cholinesterase 8 homolog A (C. elegans) (537 aa)
            score_image   0.435
USP9X
ubiquitin specific peptidase 9, X-linked; Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important role regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Essential component of TGF-beta/BMP signaling cascade. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Specifically hydrolyzes both ’Lys-29’- and ’Lys-33’-linked polyubiquitins chains. Specificall [...] (2570 aa)
            score_image   0.421
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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