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STRINGSTRING
HIST1H4K HIST1H4K HIST2H4B HIST2H4B HIST1H2BC HIST1H2BC HIST1H4E HIST1H4E HIST1H2BG HIST1H2BG HIST1H3D HIST1H3D HIST4H4 HIST4H4 HIST1H2AL HIST1H2AL UBC UBC HIST1H4D HIST1H4D HIST1H4L HIST1H4L
"HIST1H3D" - histone cluster 1, H3d in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HIST1H3Dhistone cluster 1, H3d (136 aa)    
Predicted Functional Partners:
UBC
ubiquitin C (685 aa)
      score_image score_image   score_image   0.939
HIST1H2BG
histone cluster 1, H2bg (126 aa)
      score_image score_image   score_image   0.851
HIST1H2AL
histone cluster 1, H2al (130 aa)
      score_image score_image   score_image   0.847
HIST1H4K
histone cluster 1, H4k (103 aa)
      score_image score_image   score_image   0.845
HIST1H2BC
histone cluster 1, H2bc (126 aa)
      score_image score_image   score_image   0.839
HIST1H4D
histone cluster 1, H4d (103 aa)
      score_image score_image   score_image   0.834
HIST1H4L
histone cluster 1, H4l (103 aa)
      score_image score_image   score_image   0.831
HIST2H4B
histone cluster 2, H4b (103 aa)
      score_image score_image   score_image   0.831
HIST1H4E
histone cluster 1, H4e (103 aa)
      score_image score_image   score_image   0.831
HIST4H4
histone cluster 4, H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (103 aa)
      score_image score_image   score_image   0.831
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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