node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APBA2 | CASK | ENSP00000453144 | ENSP00000367408 | amyloid beta (A4) precursor protein-binding, family A, member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.982 |
CASK | APBA2 | ENSP00000367408 | ENSP00000453144 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | amyloid beta (A4) precursor protein-binding, family A, member 2; Putative function in synaptic vesicle exocytosis by binding to STXBP1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the beta-amyloid precursor protein (APP) and hence formation of beta-APP | 0.982 |
CASK | CASKIN1 | ENSP00000367408 | ENSP00000345436 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity) | 0.992 |
CASK | DLG1 | ENSP00000367408 | ENSP00000345731 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | discs, large homolog 1 (Drosophila) | 0.969 |
CASK | LIN7A | ENSP00000367408 | ENSP00000447488 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | lin-7 homolog A (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.999 |
CASK | LIN7B | ENSP00000367408 | ENSP00000221459 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | lin-7 homolog B (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.990 |
CASK | LIN7C | ENSP00000367408 | ENSP00000278193 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | lin-7 homolog C (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.981 |
CASK | SDC1 | ENSP00000367408 | ENSP00000254351 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | syndecan 1; Cell surface proteoglycan that bears both heparan sulfate and chondroitin sulfate and that links the cytoskeleton to the interstitial matrix | 0.969 |
CASK | SDC2 | ENSP00000367408 | ENSP00000307046 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | syndecan 2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity) | 0.998 |
CASK | SDC3 | ENSP00000367408 | ENSP00000344468 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | syndecan 3; Cell surface proteoglycan that may bear heparan sulfate (By similarity). May have a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism | 0.971 |
CASK | SPATA2 | ENSP00000367408 | ENSP00000289431 | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | spermatogenesis associated 2; May have a role in the regulation of spermatogenesis | 0.999 |
CASKIN1 | CASK | ENSP00000345436 | ENSP00000367408 | CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity) | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.992 |
CASKIN1 | LIN7A | ENSP00000345436 | ENSP00000447488 | CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity) | lin-7 homolog A (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.545 |
CASKIN1 | SDC2 | ENSP00000345436 | ENSP00000307046 | CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity) | syndecan 2; Cell surface proteoglycan that bears heparan sulfate. Regulates dendritic arbor morphogenesis (By similarity) | 0.487 |
DLG1 | CASK | ENSP00000345731 | ENSP00000367408 | discs, large homolog 1 (Drosophila) | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.969 |
DLG1 | LIN7A | ENSP00000345731 | ENSP00000447488 | discs, large homolog 1 (Drosophila) | lin-7 homolog A (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.801 |
DLG1 | LIN7B | ENSP00000345731 | ENSP00000221459 | discs, large homolog 1 (Drosophila) | lin-7 homolog B (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.469 |
DLG1 | LIN7C | ENSP00000345731 | ENSP00000278193 | discs, large homolog 1 (Drosophila) | lin-7 homolog C (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | 0.916 |
LIN7A | CASK | ENSP00000447488 | ENSP00000367408 | lin-7 homolog A (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | calcium/calmodulin-dependent serine protein kinase (MAGUK family) | 0.999 |
LIN7A | CASKIN1 | ENSP00000447488 | ENSP00000345436 | lin-7 homolog A (C. elegans); Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may [...] | CASK interacting protein 1; May link the scaffolding protein CASK to downstream intracellular effectors (By similarity) | 0.545 |