node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B4GALT1 | GALE | ENSP00000369055 | ENSP00000363621 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | 0.900 |
B4GALT1 | GALT | ENSP00000369055 | ENSP00000368119 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | galactose-1-phosphate uridylyltransferase | 0.900 |
B4GALT2 | GALE | ENSP00000310696 | ENSP00000363621 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | 0.900 |
B4GALT2 | GALT | ENSP00000310696 | ENSP00000368119 | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | galactose-1-phosphate uridylyltransferase | 0.900 |
GALE | B4GALT1 | ENSP00000363621 | ENSP00000369055 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | 0.900 |
GALE | B4GALT2 | ENSP00000363621 | ENSP00000310696 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | UDP-Gal-betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 | 0.900 |
GALE | GALK1 | ENSP00000363621 | ENSP00000225614 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | galactokinase 1; Major enzyme for galactose metabolism | 0.996 |
GALE | GALK2 | ENSP00000363621 | ENSP00000453129 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates | 0.988 |
GALE | GALM | ENSP00000363621 | ENSP00000272252 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) | 0.959 |
GALE | GALT | ENSP00000363621 | ENSP00000368119 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | galactose-1-phosphate uridylyltransferase | 0.999 |
GALE | UGDH | ENSP00000363621 | ENSP00000319501 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate | 0.980 |
GALE | UGP2 | ENSP00000363621 | ENSP00000338703 | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | UDP-glucose pyrophosphorylase 2; Plays a central role as a glucosyl donor in cellular metabolic pathways | 0.958 |
GALK1 | GALE | ENSP00000225614 | ENSP00000363621 | galactokinase 1; Major enzyme for galactose metabolism | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | 0.996 |
GALK1 | GALK2 | ENSP00000225614 | ENSP00000453129 | galactokinase 1; Major enzyme for galactose metabolism | galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates | 0.825 |
GALK1 | GALM | ENSP00000225614 | ENSP00000272252 | galactokinase 1; Major enzyme for galactose metabolism | galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) | 0.998 |
GALK1 | GALT | ENSP00000225614 | ENSP00000368119 | galactokinase 1; Major enzyme for galactose metabolism | galactose-1-phosphate uridylyltransferase | 0.999 |
GALK1 | UGP2 | ENSP00000225614 | ENSP00000338703 | galactokinase 1; Major enzyme for galactose metabolism | UDP-glucose pyrophosphorylase 2; Plays a central role as a glucosyl donor in cellular metabolic pathways | 0.479 |
GALK2 | GALE | ENSP00000453129 | ENSP00000363621 | galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates | UDP-galactose-4-epimerase; Catalyzes two distinct but analogous reactions- the epimerization of UDP-glucose to UDP-galactose and the epimerization of UDP-N-acetylglucosamine to UDP-N- acetylgalactosamine | 0.988 |
GALK2 | GALK1 | ENSP00000453129 | ENSP00000225614 | galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates | galactokinase 1; Major enzyme for galactose metabolism | 0.825 |
GALK2 | GALM | ENSP00000453129 | ENSP00000272252 | galactokinase 2; Acts on GalNAc. Also acts as a galactokinase when galactose is present at high concentrations. May be involved in a salvage pathway for the reutilization of free GalNAc derived from the degradation of complex carbohydrates | galactose mutarotase (aldose 1-epimerase); Mutarotase converts alpha-aldose to the beta-anomer. It is active on D-glucose, L-arabinose, D-xylose, D-galactose, maltose and lactose (By similarity) | 0.984 |