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VDAC3 VDAC3 VDAC2 VDAC2 AKR1A1 AKR1A1 AKR1B1 AKR1B1 GK GK AGPAT6 AGPAT6 GPAM GPAM AQP7 AQP7 AGPAT9 AGPAT9 GPD2 GPD2 GPAT2 GPAT2
"GK" - glycerol kinase in Homo sapiens
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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protein of unknown 3D structure
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Predicted Interactions
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Score
GKglycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism (553 aa)    
Predicted Functional Partners:
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial) (727 aa)
score_image score_image score_image score_image     score_image   0.950
VDAC3
voltage-dependent anion channel 3; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules (By similarity) (284 aa)
            score_image   0.939
AGPAT6
1-acylglycerol-3-phosphate O-acyltransferase 6 (lysophosphatidic acid acyltransferase, zeta); Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Active against both saturated and unsaturated long- chain fatty acyl-CoAs (456 aa)
          score_image score_image   0.931
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis. Overexpression activates the mTOR pathway (434 aa)
          score_image score_image   0.925
VDAC2
voltage-dependent anion channel 2; Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective (309 aa)
            score_image   0.926
GPAM
glycerol-3-phosphate acyltransferase, mitochondrial; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis (828 aa)
          score_image score_image   0.920
AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase); Catalyzes the NADPH-dependent reduction of a variety of aromatic and aliphatic aldehydes to their corresponding alcohols. Catalyzes the reduction of mevaldate to mevalonic acid and of glyceraldehyde to glycerol. Has broad substrate specificity. In vitro substrates include succinic semialdehyde, 4- nitrobenzaldehyde, 1,2-naphthoquinone, methylglyoxal, and D- glucuronic acid. Plays a role in the activation of procarcinogens, such as polycyclic aromatic hydrocarbon trans-dihydrodiols, and in the metabolism of various xenobiotic [...] (325 aa)
          score_image score_image   0.910
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial; Esterifies acyl-group from acyl-ACP to the sn-1 position of glycerol-3-phosphate, an essential step in glycerolipid biosynthesis (By similarity) (795 aa)
          score_image score_image   0.909
AQP7
aquaporin 7; Forms a channel for water and glycerol (342 aa)
score_image     score_image     score_image   0.908
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase); Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies (316 aa)
          score_image score_image   0.907
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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