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STRINGSTRING
EIF2A EIF2A MSS51 MSS51 ENSG00000212857 ENSG00000212857 CXorf58 CXorf58 KLHL34 KLHL34 DMRTC1 DMRTC1 MORC4 MORC4 ZXDB ZXDB NDUFAF7 NDUFAF7
"KLHL34" - kelch-like 34 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KLHL34kelch-like 34 (Drosophila) (644 aa)    
Predicted Functional Partners:
MSS51
MSS51 mitochondrial translational activator homolog (S. cerevisiae) (460 aa)
            score_image   0.503
ENSG00000212857
Uncharacterized protein DKFZp434B061 (555 aa)
            score_image   0.499
EIF2A
eukaryotic translation initiation factor 2A, 65kDa; Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF- 2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon- dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (585 aa)
            score_image   0.471
CXorf58
chromosome X open reading frame 58 (332 aa)
            score_image   0.459
DMRTC1
DMRT-like family C1 (192 aa)
            score_image   0.457
ZXDB
zinc finger, X-linked, duplicated B; Cooperates with CIITA to promote transcription of MHC class I and MHC class II genes (By similarity) (803 aa)
      score_image     score_image   0.421
NDUFAF7
NADH dehydrogenase (ubiquinone) complex I, assembly factor 7; Involved in the assembly or stability of mitochondrial NADH-ubiquinone oxidoreductase complex (complex I) (441 aa)
            score_image   0.418
MORC4
MORC family CW-type zinc finger 4 (937 aa)
            score_image   0.407
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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