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STRINGSTRING
CXorf23 CXorf23 MAP7D2 MAP7D2 C16orf45 C16orf45 EIF1AX EIF1AX PNMAL1 PNMAL1 TMEM59L TMEM59L UBC UBC PJA1 PJA1 PJA2 PJA2
"MAP7D2" - MAP7 domain containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MAP7D2MAP7 domain containing 2 (773 aa)    
Predicted Functional Partners:
CXorf23
chromosome X open reading frame 23 (682 aa)
            score_image   0.650
PNMAL1
paraneoplastic Ma antigen family-like 1 (439 aa)
            score_image   0.596
C16orf45
chromosome 16 open reading frame 45 (204 aa)
            score_image   0.596
TMEM59L
transmembrane protein 59-like; Modulates the O-glycosylation and complex N- glycosylation steps occurring during the Golgi maturation of APP. Inhibits APP transport to the cell surface and further shedding (342 aa)
            score_image   0.596
PJA1
praja ring finger 1, E3 ubiquitin protein ligase; Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome (By similarity). May be involved in protein sorting (643 aa)
            score_image   0.483
PJA2
praja ring finger 2, E3 ubiquitin protein ligase; Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes (708 aa)
            score_image   0.483
UBC
ubiquitin C (685 aa)
        score_image       0.483
EIF1AX
eukaryotic translation initiation factor 1A, X-linked; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits (144 aa)
            score_image   0.474
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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