| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ATP6AP1L | ATP6V0A1 | ENSP00000369513 | ENSP00000264649 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | 0.553 |
| ATP6AP1L | ATP6V0A2 | ENSP00000369513 | ENSP00000332247 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH | 0.553 |
| ATP6AP1L | ATP6V0A4 | ENSP00000369513 | ENSP00000253856 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | 0.553 |
| ATP6AP1L | ATP6V0D1 | ENSP00000369513 | ENSP00000290949 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.578 |
| ATP6AP1L | ATP6V0D2 | ENSP00000369513 | ENSP00000285393 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.578 |
| ATP6AP1L | ATP6V1B1 | ENSP00000369513 | ENSP00000234396 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.583 |
| ATP6AP1L | ATP6V1B2 | ENSP00000369513 | ENSP00000276390 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.583 |
| ATP6AP1L | ATP6V1E1 | ENSP00000369513 | ENSP00000253413 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.621 |
| ATP6AP1L | ATP6V1E2 | ENSP00000369513 | ENSP00000304891 | ATPase, H+ transporting, lysosomal accessory protein 1-like | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity) | 0.621 |
| ATP6AP1L | TCIRG1 | ENSP00000369513 | ENSP00000265686 | ATPase, H+ transporting, lysosomal accessory protein 1-like | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3; Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation | 0.553 |
| ATP6V0A1 | ATP6AP1L | ENSP00000264649 | ENSP00000369513 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal accessory protein 1-like | 0.553 |
| ATP6V0A1 | ATP6V0A2 | ENSP00000264649 | ENSP00000332247 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal V0 subunit a2; Part of the proton channel of V-ATPases. Essential component of the endosomal pH-sensing machinery. May play a role in maintaining the Golgi functions, such as glycosylation maturation, by controlling the Golgi pH | 0.903 |
| ATP6V0A1 | ATP6V0A4 | ENSP00000264649 | ENSP00000253856 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal V0 subunit a4; Part of the proton channel of the V-ATPase that is involved in normal vectorial acid transport into the urine by the kidney (By similarity) | 0.902 |
| ATP6V0A1 | ATP6V0D1 | ENSP00000264649 | ENSP00000290949 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.997 |
| ATP6V0A1 | ATP6V0D2 | ENSP00000264649 | ENSP00000285393 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2; Subunit of the integral membrane V0 complex of vacuolar ATPase. Vacuolar ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells, thus providing most of the energy required for transport processes in the vacuolar system. May play a role in coupling of proton transport and ATP hydrolysis (By similarity) | 0.997 |
| ATP6V0A1 | ATP6V1B1 | ENSP00000264649 | ENSP00000234396 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.999 |
| ATP6V0A1 | ATP6V1B2 | ENSP00000264649 | ENSP00000276390 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2; Non-catalytic subunit of the peripheral V1 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.997 |
| ATP6V0A1 | ATP6V1E1 | ENSP00000264649 | ENSP00000253413 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells | 0.998 |
| ATP6V0A1 | ATP6V1E2 | ENSP00000264649 | ENSP00000304891 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E2; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. This isoform is essential for energy coupling involved in acidification of acrosome (By similarity) | 0.996 |
| ATP6V0A1 | TCIRG1 | ENSP00000264649 | ENSP00000265686 | ATPase, H+ transporting, lysosomal V0 subunit a1; Required for assembly and activity of the vacuolar ATPase. Potential role in differential targeting and regulation of the enzyme for a specific organelle (By similarity) | T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3; Part of the proton channel of V-ATPases (By similarity). Seems to be directly involved in T-cell activation | 0.905 |
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