| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LUC7L | NCBP1 | ENSP00000293872 | ENSP00000364289 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | nuclear cap binding protein subunit 1, 80kDa; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5’-end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. T [...] | 0.880 |
| LUC7L | PRPF39 | ENSP00000293872 | ENSP00000348010 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae); Involved in pre-mRNA splicing (By similarity) | 0.940 |
| LUC7L | PRPF40B | ENSP00000293872 | ENSP00000369634 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae); May be involved in pre-mRNA splicing | 0.863 |
| LUC7L | RBM25 | ENSP00000293872 | ENSP00000261973 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | RNA binding motif protein 25 | 0.937 |
| LUC7L | SNRNP70 | ENSP00000293872 | ENSP00000472998 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein 70kDa (U1) | 0.957 |
| LUC7L | SNRPC | ENSP00000293872 | ENSP00000244520 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein polypeptide C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5’ splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5’ splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5’ splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5’ end of the U1 snRNA and the 5’ splice-site region | 0.954 |
| LUC7L | SNRPD1 | ENSP00000293872 | ENSP00000300413 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein D1 polypeptide 16kDa; May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA | 0.837 |
| LUC7L | SNRPD3 | ENSP00000293872 | ENSP00000215829 | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein D3 polypeptide 18kDa; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner | 0.870 |
| LUC7L2 | NCBP1 | ENSP00000347005 | ENSP00000364289 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | nuclear cap binding protein subunit 1, 80kDa; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5’-end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. T [...] | 0.849 |
| LUC7L2 | PRPF39 | ENSP00000347005 | ENSP00000348010 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae); Involved in pre-mRNA splicing (By similarity) | 0.938 |
| LUC7L2 | PRPF40B | ENSP00000347005 | ENSP00000369634 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae); May be involved in pre-mRNA splicing | 0.863 |
| LUC7L2 | RBM25 | ENSP00000347005 | ENSP00000261973 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | RNA binding motif protein 25 | 0.875 |
| LUC7L2 | SNRNP70 | ENSP00000347005 | ENSP00000472998 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein 70kDa (U1) | 0.962 |
| LUC7L2 | SNRPC | ENSP00000347005 | ENSP00000244520 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein polypeptide C; Component of the U1 snRNP, which is essential for recognition of the pre-mRNA 5’ splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5’ splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5’ splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates E complex formation by stabilizing the base pairing of the 5’ end of the U1 snRNA and the 5’ splice-site region | 0.940 |
| LUC7L2 | SNRPD1 | ENSP00000347005 | ENSP00000300413 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein D1 polypeptide 16kDa; May act as a charged protein scaffold to promote snRNP assembly or strengthen snRNP-snRNP interactions through nonspecific electrostatic contacts with RNA | 0.823 |
| LUC7L2 | SNRPD3 | ENSP00000347005 | ENSP00000215829 | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | small nuclear ribonucleoprotein D3 polypeptide 18kDa; Appears to function in the U7 snRNP complex that is involved in histone 3’-end processing. Binds to the downstream cleavage product (DCP) of histone pre-mRNA in a U7 snRNP dependent manner | 0.848 |
| NCBP1 | LUC7L | ENSP00000364289 | ENSP00000293872 | nuclear cap binding protein subunit 1, 80kDa; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5’-end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. T [...] | LUC7-like (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | 0.880 |
| NCBP1 | LUC7L2 | ENSP00000364289 | ENSP00000347005 | nuclear cap binding protein subunit 1, 80kDa; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5’-end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. T [...] | LUC7-like 2 (S. cerevisiae); May bind to RNA via its Arg/Ser-rich domain | 0.849 |
| NCBP1 | PRPF39 | ENSP00000364289 | ENSP00000348010 | nuclear cap binding protein subunit 1, 80kDa; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5’-end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. T [...] | PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae); Involved in pre-mRNA splicing (By similarity) | 0.955 |
| NCBP1 | PRPF40B | ENSP00000364289 | ENSP00000369634 | nuclear cap binding protein subunit 1, 80kDa; Component of the cap-binding complex (CBC), which binds cotranscriptionally to the 5’-cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense-mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus via its interaction with ALYREF/THOC4/ALY, leading to the recruitment of the mRNA export machinery to the 5’-end of mRNA and to mRNA export in a 5’ to 3’ direction through the nuclear pore. T [...] | PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae); May be involved in pre-mRNA splicing | 0.862 |
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