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STRINGSTRING
AKR1CL1 AKR1CL1 SMIM5 SMIM5 TUBAL3 TUBAL3 MAPRE2 MAPRE2 MAPRE3 MAPRE3 KIF18B KIF18B KIF19 KIF19 CKAP5 CKAP5 TBCB TBCB MAPRE1 MAPRE1 CCDC88B CCDC88B
"TUBAL3" - tubulin, alpha-like 3 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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[Homology]
Score
TUBAL3tubulin, alpha-like 3 (446 aa)    
Predicted Functional Partners:
CKAP5
cytoskeleton associated protein 5; Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles (2032 aa)
        score_image   score_image   0.731
MAPRE1
microtubule-associated protein, RP/EB family, member 1; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (268 aa)
        score_image   score_image   0.720
MAPRE2
microtubule-associated protein, RP/EB family, member 2; May be involved in microtubule polymerization, and spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity) (327 aa)
        score_image   score_image   0.720
MAPRE3
microtubule-associated protein, RP/EB family, member 3; Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration (By similarity) (281 aa)
        score_image   score_image   0.720
TBCB
tubulin folding cofactor B; Binds to alpha-tubulin folding intermediates after their interaction with cytosolic chaperonin in the pathway leading from newly synthesized tubulin to properly folded heterodimer. Involved in regulation of tubulin heterodimer dissociation. May function as a negative regulator of axonal growth (244 aa)
        score_image   score_image   0.682
CCDC88B
coiled-coil domain containing 88B (1476 aa)
        score_image   score_image   0.658
AKR1CL1
aldo-keto reductase family 1, member C-like 1 (152 aa)
            score_image   0.648
SMIM5
small integral membrane protein 5 (77 aa)
            score_image   0.632
KIF19
kinesin family member 19; Plus end-directed microtubule-dependent motor protein that regulates the length of motile cilia by mediating depolymerization of microtubules at ciliary tips (By similarity) (998 aa)
        score_image   score_image   0.627
KIF18B
kinesin family member 18B; In complex with KIF2C, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells. Its major role may be to transport KIF2C and/or MAPRE1 along microtubules (855 aa)
        score_image   score_image   0.627
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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