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MORC4 MORC4 MINK1 MINK1 MORC3 MORC3 SCAF4 SCAF4 C2CD2 C2CD2 MRPL39 MRPL39 AKIP1 AKIP1 SETD4 SETD4 DNAJC28 DNAJC28 LCA5 LCA5 PRDM15 PRDM15
"C2CD2" - C2 calcium-dependent domain containing 2 in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
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Cooccurence
Coexpression
Experiments
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Textmining
[Homology]
Score
C2CD2C2 calcium-dependent domain containing 2 (696 aa)    
Predicted Functional Partners:
MORC3
MORC family CW-type zinc finger 3 (939 aa)
            score_image   0.629
SETD4
SET domain containing 4 (440 aa)
            score_image   0.587
SCAF4
SR-related CTD-associated factor 4; May act to physically and functionally link transcription and pre-mRNA processing (By similarity) (1147 aa)
            score_image   0.574
MRPL39
mitochondrial ribosomal protein L39 (353 aa)
            score_image   0.572
LCA5
Leber congenital amaurosis 5; Might be involved in minus end-directed microtubule transport (697 aa)
            score_image   0.495
PRDM15
PR domain containing 15; May be involved in transcriptional regulation (1507 aa)
            score_image   0.495
MORC4
MORC family CW-type zinc finger 4 (937 aa)
            score_image   0.493
AKIP1
A kinase (PRKA) interacting protein 1; Enhances NF-kappa-B transcriptional activity by regulating the nuclear localization of the NF-kappa-B subunit RELA and promoting the phosphorylation of RELA by PRKACA. Regulates the effect of the cAMP-dependent protein kinase signaling pathway on the NF-kappa-B activation cascade (210 aa)
            score_image   0.485
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28; May have a role in protein folding or as a chaperone (388 aa)
            score_image   0.483
MINK1
misshapen-like kinase 1; Serine/threonine kinase which acts as a negative regulator of Ras-related Rap2-mediated signal transduction to control neuronal structure and AMPA receptor trafficking. Required for normal synaptic density, dendrite complexity, as well as surface AMPA receptor expression in hippocampal neurons. Can activate the JNK and MAPK14/p38 pathways and mediates stimulation of the stress-activated protein kinase MAPK14/p38 MAPK downstream of the Raf/ERK pathway. Phosphorylates- TANC1 upon stimulation by RAP2A, MBP and SMAD1. Has an essential function in negative selection [...] (1332 aa)
            score_image   0.459
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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