node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABCG1 | COL4A3BP | ENSP00000354995 | ENSP00000369862 | ATP-binding cassette, sub-family G (WHITE), member 1 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.818 |
COL4A3 | COL4A3BP | ENSP00000379823 | ENSP00000369862 | collagen, type IV, alpha 3 (Goodpasture antigen) | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.889 |
COL4A3BP | ABCG1 | ENSP00000369862 | ENSP00000354995 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | ATP-binding cassette, sub-family G (WHITE), member 1 | 0.818 |
COL4A3BP | COL4A3 | ENSP00000369862 | ENSP00000379823 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | collagen, type IV, alpha 3 (Goodpasture antigen) | 0.889 |
COL4A3BP | CSNK1G2 | ENSP00000369862 | ENSP00000255641 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | casein kinase 1, gamma 2; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteas [...] | 0.827 |
COL4A3BP | GIT1 | ENSP00000369862 | ENSP00000378338 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | G protein-coupled receptor kinase interacting ArfGAP 1; GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine- phosphorylated paxillin in cytoplasmic complexes | 0.802 |
COL4A3BP | ITGB3BP | ENSP00000369862 | ENSP00000360133 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | integrin beta 3 binding protein (beta3-endonexin) | 0.761 |
COL4A3BP | MARK2 | ENSP00000369862 | ENSP00000385751 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...] | 0.740 |
COL4A3BP | PRKD1 | ENSP00000369862 | ENSP00000333568 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...] | 0.947 |
COL4A3BP | PRKD3 | ENSP00000369862 | ENSP00000234179 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | protein kinase D3; Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity) | 0.770 |
COL4A3BP | RTN3 | ENSP00000369862 | ENSP00000344106 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | reticulon 3 | 0.827 |
COL4A3BP | VAPA | ENSP00000369862 | ENSP00000345656 | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa; May play a role in vesicle trafficking | 0.910 |
CSNK1G2 | COL4A3BP | ENSP00000255641 | ENSP00000369862 | casein kinase 1, gamma 2; Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling (By similarity). Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteas [...] | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.827 |
GIT1 | COL4A3BP | ENSP00000378338 | ENSP00000369862 | G protein-coupled receptor kinase interacting ArfGAP 1; GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine- phosphorylated paxillin in cytoplasmic complexes | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.802 |
GIT1 | PRKD3 | ENSP00000378338 | ENSP00000234179 | G protein-coupled receptor kinase interacting ArfGAP 1; GTPase-activating protein for the ADP ribosylation factor family. May serve as a scaffold to bring together molecules to form signaling modules controlling vesicle trafficking, adhesion and cytoskeletal organization. Increases the speed of cell migration, as well as the size and rate of formation of protrusions, possibly by targeting PAK1 to adhesions and the leading edge of lamellipodia. Sequesters inactive non-tyrosine- phosphorylated paxillin in cytoplasmic complexes | protein kinase D3; Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress (By similarity) | 0.804 |
ITGB3BP | COL4A3BP | ENSP00000360133 | ENSP00000369862 | integrin beta 3 binding protein (beta3-endonexin) | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.761 |
MARK2 | COL4A3BP | ENSP00000385751 | ENSP00000369862 | MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...] | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.740 |
MARK2 | PRKD1 | ENSP00000385751 | ENSP00000333568 | MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...] | protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...] | 0.608 |
PRKD1 | COL4A3BP | ENSP00000333568 | ENSP00000369862 | protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...] | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein | 0.947 |
PRKD1 | MARK2 | ENSP00000333568 | ENSP00000385751 | protein kinase D1; Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response. Phosphoryl [...] | MAP/microtubule affinity-regulating kinase 2; Serine/threonine-protein kinase involved in cell polarity and microtubule dynamics regulation. Phosphorylates CRTC2/TORC2, DCX, HDAC7, KIF13B, MAP2, MAP4, MAPT/TAU, and RAB11FIP2. Plays a key role in cell polarity by phosphorylating the microtubule-associated proteins MAP2, MAP4 and MAPT/TAU at KXGS motifs, causing detachment from microtubules, and their disassembly. Regulates epithelial cell polarity by phosphorylating RAB11FIP2. Involved in the regulation of neuronal migration through its dual activities in regulating cellular polarity an [...] | 0.608 |