FAM57B protein (Homo sapiens) - STRING network view

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Score

FAM57B

family with sequence similarity 57, member B (274 aa)

Predicted Functional Partners:

YPEL3

0.481

MAB21L1

0.450

KCTD13

0.435

CDIPT

0.414

MAB21L2

0.402

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDIPT	FAM57B	ENSP00000219789	ENSP00000369863	CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme	family with sequence similarity 57, member B	0.414
FAM57B	CDIPT	ENSP00000369863	ENSP00000219789	family with sequence similarity 57, member B	CDP-diacylglycerol--inositol 3-phosphatidyltransferase; Catalyzes the biosynthesis of phosphatidylinositol (PtdIns) as well as PtdIns-inositol exchange reaction. May thus act to reduce an excessive cellular PtdIns content. The exchange activity is due to the reverse reaction of PtdIns synthase and is dependent on CMP, which is tightly bound to the enzyme	0.414
FAM57B	KCTD13	ENSP00000369863	ENSP00000311202	family with sequence similarity 57, member B	potassium channel tetramerisation domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration	0.435
FAM57B	MAB21L1	ENSP00000369863	ENSP00000369251	family with sequence similarity 57, member B	mab-21-like 1 (C. elegans); Required for several aspects of embryonic development including normal development of the eye (By similarity)	0.450
FAM57B	MAB21L2	ENSP00000369863	ENSP00000324701	family with sequence similarity 57, member B	mab-21-like 2 (C. elegans); Required for several aspects of embryonic development including normal development of the eye (By similarity)	0.402
FAM57B	YPEL3	ENSP00000369863	ENSP00000381821	family with sequence similarity 57, member B	yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity)	0.481
KCTD13	FAM57B	ENSP00000311202	ENSP00000369863	potassium channel tetramerisation domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration	family with sequence similarity 57, member B	0.435
KCTD13	YPEL3	ENSP00000311202	ENSP00000381821	potassium channel tetramerisation domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration	yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity)	0.473
MAB21L1	FAM57B	ENSP00000369251	ENSP00000369863	mab-21-like 1 (C. elegans); Required for several aspects of embryonic development including normal development of the eye (By similarity)	family with sequence similarity 57, member B	0.450
MAB21L2	FAM57B	ENSP00000324701	ENSP00000369863	mab-21-like 2 (C. elegans); Required for several aspects of embryonic development including normal development of the eye (By similarity)	family with sequence similarity 57, member B	0.402
YPEL3	FAM57B	ENSP00000381821	ENSP00000369863	yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity)	family with sequence similarity 57, member B	0.481
YPEL3	KCTD13	ENSP00000381821	ENSP00000311202	yippee-like 3 (Drosophila); Involved in proliferation and apoptosis in myeloid precursor cells (By similarity)	potassium channel tetramerisation domain containing 13; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration	0.473

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