HAUS6 protein (Homo sapiens) - STRING network view

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protein of unknown 3D structure

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Score

HAUS6

HAUS augmin-like complex, subunit 6 (955 aa)

Predicted Functional Partners:

HAUS1

0.999

HAUS2

0.999

HAUS5

0.999

HAUS4

0.999

HAUS8

0.999

HAUS3

0.999

HAUS7

0.999

NEDD1

0.979

PLK1

0.897

NUMA1

0.863

Your Current Organism:

Homo sapiens

NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man

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a tab-delimited file describing the names, domains and annotated functions of the network proteins

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HAUS1	HAUS2	ENSP00000282058	ENSP00000260372	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.998
HAUS1	HAUS3	ENSP00000282058	ENSP00000243706	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 3; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS1	HAUS4	ENSP00000282058	ENSP00000206474	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 4; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS1	HAUS5	ENSP00000282058	ENSP00000439056	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 5; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.998
HAUS1	HAUS6	ENSP00000282058	ENSP00000369871	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 6	0.999
HAUS1	HAUS7	ENSP00000282058	ENSP00000359239	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 7; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.998
HAUS1	HAUS8	ENSP00000282058	ENSP00000253669	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 8; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS1	NUMA1	ENSP00000282058	ENSP00000377298	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions	0.686
HAUS2	HAUS1	ENSP00000260372	ENSP00000282058	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.998
HAUS2	HAUS3	ENSP00000260372	ENSP00000243706	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 3; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS2	HAUS4	ENSP00000260372	ENSP00000206474	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 4; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS2	HAUS5	ENSP00000260372	ENSP00000439056	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 5; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS2	HAUS6	ENSP00000260372	ENSP00000369871	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 6	0.999
HAUS2	HAUS7	ENSP00000260372	ENSP00000359239	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 7; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS2	HAUS8	ENSP00000260372	ENSP00000253669	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 8; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS2	NEDD1	ENSP00000260372	ENSP00000451211	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	neural precursor cell expressed, developmentally down-regulated 1; Required for mitosis progression. Promotes the nucleation of microtubules from the spindle	0.915
HAUS2	NUMA1	ENSP00000260372	ENSP00000377298	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	nuclear mitotic apparatus protein 1; Highly abundant component of the nuclear matrix where it may serve a non-mitotic structural role, occupies the majority if the nuclear volume. Required for maintenance and establishment of the mitotic spindle poles, functionning as a tether linking bulk microtubules of the spindle to centrosomes. May be involved in coordination of the alignment of the mitotic spindle to the cellular polarity axis, which is a prerequisite for asymmetric cell divisions	0.686
HAUS2	PLK1	ENSP00000260372	ENSP00000300093	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	polo-like kinase 1; Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the regulation of mitotic exit and cytokinesis. Polo-like kinase proteins acts by binding and phosphorylating proteins are that already phosphorylated on a specific motif recognized by the POLO box domains. Phosphorylates BORA, BUB1B/BUBR1, CCNB1, CDC25C, CEP55 [...]	0.900
HAUS3	HAUS1	ENSP00000243706	ENSP00000282058	HAUS augmin-like complex, subunit 3; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 1; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999
HAUS3	HAUS2	ENSP00000243706	ENSP00000260372	HAUS augmin-like complex, subunit 3; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	HAUS augmin-like complex, subunit 2; Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex	0.999

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