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STRINGSTRING
ZNF195 ZNF195 UBC UBC CARS CARS EPRS EPRS TARS TARS LARS LARS MARS MARS YARS YARS AARS AARS QARS QARS FARS2 FARS2
"CARS" - cysteinyl-tRNA synthetase in Homo sapiens
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Size
small protein node
small nodes:
protein of unknown 3D structure
large protein node
large nodes:
some 3D structure is known or predicted
Node Color
colored protein node
colored nodes:
query proteins and first shell of interactors
non-colored protein node
white nodes:
second shell of interactors
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
database edge
from curated databases
experiment edge
experimentally determined
Predicted Interactions
neighborhood edge
gene neighborhood
fusion edge
gene fusions
cooccurrence edge
gene co-occurrence
Others
textmining edge
textmining
coexpression edge
co-expression
homology edge
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CARScysteinyl-tRNA synthetase (831 aa)    
Predicted Functional Partners:
EPRS
glutamyl-prolyl-tRNA synthetase (1512 aa)
score_image     score_image     score_image   0.954
YARS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction- tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity) (528 aa)
      score_image score_image   score_image   0.937
AARS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) (968 aa)
      score_image     score_image   0.929
ZNF195
zinc finger protein 195; May be involved in transcriptional regulation (629 aa)
            score_image   0.910
MARS
methionyl-tRNA synthetase (900 aa)
      score_image     score_image   0.896
QARS
glutaminyl-tRNA synthetase (775 aa)
score_image     score_image     score_image   0.858
LARS
leucyl-tRNA synthetase; Catalyzes the specific attachment of an amino acid to its cognate tRNA in a two step reaction- the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Exhibits a post-transfer editing activity to hydrolyze mischarged tRNAs (1176 aa)
score_image     score_image     score_image   0.841
TARS
threonyl-tRNA synthetase (723 aa)
score_image     score_image     score_image   0.831
FARS2
phenylalanyl-tRNA synthetase 2, mitochondrial; Catalyzes direct attachment of p-Tyr (Tyr) to tRNAPhe. Permits also, with a lower efficiency, the attachment of m-Tyr to tRNAPhe, thereby opening the way for delivery of the misacylated tRNA to the ribosome and incorporation of ROS-damaged amino acid into proteins (451 aa)
      score_image     score_image   0.827
UBC
ubiquitin C (685 aa)
        score_image   score_image   0.802
Your Current Organism:
Homo sapiens
NCBI taxonomy Id: 9606
Other names: H. sapiens, Homo, Homo sapiens, human, man
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